The Resource Adhesion G Protein-coupled Receptors : Molecular, Physiological and Pharmacological Principles in Health and Disease, edited by Tobias Langenhan, Torsten Schöneberg, (electronic resource)

Adhesion G Protein-coupled Receptors : Molecular, Physiological and Pharmacological Principles in Health and Disease, edited by Tobias Langenhan, Torsten Schöneberg, (electronic resource)

Label
Adhesion G Protein-coupled Receptors : Molecular, Physiological and Pharmacological Principles in Health and Disease
Title
Adhesion G Protein-coupled Receptors
Title remainder
Molecular, Physiological and Pharmacological Principles in Health and Disease
Statement of responsibility
edited by Tobias Langenhan, Torsten Schöneberg
Contributor
Editor
Editor
Subject
Language
eng
Summary
Latest research on Adhesion GPCRs has unearthed surprising revelations about the events that govern the signal transduction of these receptor molecules and the cellular and organ requirements for these signals. Unexpected and unprecedented findings suggest that Adhesion GPCRs constitute a group of receptors that sense mechanical stimuli and transcode them into metabotropic signals through the action of a novel activation paradigm. Interdisciplinary efforts transcending many areas of biomedical research including pharmacology, physiology, genetics, cell biology, structural biology, biochemistry and bioinformatics were necessary to unveil these fundamental properties. The scientific leaders in the field that carried this research effort have teamed up here to provide a comprehensive overview of our current understanding, how Adhesion GPCRs signal and how these receptors shape organ structure and function
Member of
Dewey number
615
http://bibfra.me/vocab/relation/httpidlocgovvocabularyrelatorsedt
  • Rx-dXgbvot8
  • AAE9hIggHMM
Image bit depth
0
LC call number
RM1-950
Literary form
non fiction
Nature of contents
dictionaries
http://library.link/vocab/relatedWorkOrContributorName
  • Langenhan, Tobias.
  • Schöneberg, Torsten.
Series statement
Handbook of Experimental Pharmacology,
Series volume
234
http://library.link/vocab/subjectName
  • Toxicology
  • Human physiology
  • Human genetics
  • Cytology
  • Biochemistry
  • Pharmacology/Toxicology
  • Human Physiology
  • Human Genetics
  • Cell Biology
  • Medical Biochemistry
Label
Adhesion G Protein-coupled Receptors : Molecular, Physiological and Pharmacological Principles in Health and Disease, edited by Tobias Langenhan, Torsten Schöneberg, (electronic resource)
Instantiates
Publication
Antecedent source
mixed
Bibliography note
Includes bibliographical references at the end of each chapters and index
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
PART I. Molecular and Pharmacological Properties of Adhesion GPCRs:-Classification, Nomenclature and Structural Aspects of Adhesion GPCRs -- 7TM Domain Structure of Adhesion GPCRs -- Understanding the Structural Basis of Adhesion GPCR Functions.-Control of Adhesion GPCR Function Through Proteolytic Processing.-Tethered Agonism: A Common Activation Mechanism of Adhesion GPCRs -- Versatile Signaling Activity of Adhesion GPCRs -- Adhesion GPCR-Related Protein Networks.-The Relevance of Genomic Signatures at Adhesion GPCR Loci in Humans -- PART II: Adhesion GPCRs as Pharmakotargets in Organ Function and Development -- Adhesion GPCRs as a Putative Class of Metabotropic Mechanosensors -- Adhesion GPCRs Govern Polarity of Epithelia and Cell Migration -- Adhesion GPCRs as Novel Actors in Neural and Glial Cell Functions: From Synaptogenesis to Myelination.-Control of Skeletal Muscle Cell Growth and Size Through Adhesion GPCRs -- Adhesion GPCR Function in Pulmonary Development and Disease.-Adhesion GPCRs as Modulators of Immune Cell Function.-Heart Development, Angiogenesis, and Blood-Brain Barrier Function is Modulated by Adhesion GPCRs.-Adhesion GPCRs in Tumorigenesis
Dimensions
unknown
Extent
1 online resource (XIV, 403 p. 68 illus., 67 illus. in color.)
File format
multiple file formats
Form of item
online
Isbn
9783319415239
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other control number
10.1007/978-3-319-41523-9
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote
System control number
  • (CKB)3710000000943124
  • (DE-He213)978-3-319-41523-9
  • (MiAaPQ)EBC4740960
  • (EXLCZ)993710000000943124
Label
Adhesion G Protein-coupled Receptors : Molecular, Physiological and Pharmacological Principles in Health and Disease, edited by Tobias Langenhan, Torsten Schöneberg, (electronic resource)
Publication
Antecedent source
mixed
Bibliography note
Includes bibliographical references at the end of each chapters and index
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
PART I. Molecular and Pharmacological Properties of Adhesion GPCRs:-Classification, Nomenclature and Structural Aspects of Adhesion GPCRs -- 7TM Domain Structure of Adhesion GPCRs -- Understanding the Structural Basis of Adhesion GPCR Functions.-Control of Adhesion GPCR Function Through Proteolytic Processing.-Tethered Agonism: A Common Activation Mechanism of Adhesion GPCRs -- Versatile Signaling Activity of Adhesion GPCRs -- Adhesion GPCR-Related Protein Networks.-The Relevance of Genomic Signatures at Adhesion GPCR Loci in Humans -- PART II: Adhesion GPCRs as Pharmakotargets in Organ Function and Development -- Adhesion GPCRs as a Putative Class of Metabotropic Mechanosensors -- Adhesion GPCRs Govern Polarity of Epithelia and Cell Migration -- Adhesion GPCRs as Novel Actors in Neural and Glial Cell Functions: From Synaptogenesis to Myelination.-Control of Skeletal Muscle Cell Growth and Size Through Adhesion GPCRs -- Adhesion GPCR Function in Pulmonary Development and Disease.-Adhesion GPCRs as Modulators of Immune Cell Function.-Heart Development, Angiogenesis, and Blood-Brain Barrier Function is Modulated by Adhesion GPCRs.-Adhesion GPCRs in Tumorigenesis
Dimensions
unknown
Extent
1 online resource (XIV, 403 p. 68 illus., 67 illus. in color.)
File format
multiple file formats
Form of item
online
Isbn
9783319415239
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other control number
10.1007/978-3-319-41523-9
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote
System control number
  • (CKB)3710000000943124
  • (DE-He213)978-3-319-41523-9
  • (MiAaPQ)EBC4740960
  • (EXLCZ)993710000000943124

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