The Resource Adipose Tissue and Cancer, edited by Mikhail G. Kolonin, (electronic resource)

Adipose Tissue and Cancer, edited by Mikhail G. Kolonin, (electronic resource)

Label
Adipose Tissue and Cancer
Title
Adipose Tissue and Cancer
Statement of responsibility
edited by Mikhail G. Kolonin
Contributor
Editor
Editor
Subject
Language
  • eng
  • eng
Summary
The pathophysiology underlying the relationship between obesity and cancer is complex and incompletely understood. Progression of certain cancers has been shown to accelerate in obese patients irrespective of their lifestyle and diet. Because obesity is manifested by overgrowth of white adipose tissue, it has been proposed that adipose tissue has a direct effect on cancer progression. Adipose tissue is composed of several types of cells secreting numerous soluble factors collectively termed adipokines. In addition, infiltration of the immune system cells in obesity leads to increased production of a number of inflammatory factors by adipose tissue, thus contributing to the establishment of the metabolic syndrome. Endocrine signaling by adipose tissue-derived molecules has been shown to promote cancer in animal models, matching clinical associations. Recent studies have shown that cells from adipose tissue are capable of trafficking to tumors, thus enabling paracrine action of adipokines from within the tumor microenvironment. Increased tumor vascularization, immune system suppression and direct effects on malignant cell survival and proliferation have been investigated as mechanisms regulated by adipokines. This volume will discuss clinical and experimental data pointing to the role of adipose tissue in cancer and to dissect individual mechanisms through which adipose tissue excess or restriction could influence cancer progression
Dewey number
616.99407
http://bibfra.me/vocab/relation/httpidlocgovvocabularyrelatorsedt
kiDpgSQSZ0w
Language note
English
LC call number
RC261-271
Literary form
non fiction
Nature of contents
dictionaries
http://library.link/vocab/relatedWorkOrContributorName
Kolonin, Mikhail G.
http://library.link/vocab/subjectName
  • Oncology
  • Lipids
  • Cytology
  • Cancer Research
  • Lipidology
  • Cell Biology
Label
Adipose Tissue and Cancer, edited by Mikhail G. Kolonin, (electronic resource)
Instantiates
Publication
Note
Description based upon print version of record
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
cr
Content category
text
Content type code
txt
Contents
Preface: Obesity, Adipose Tissue and Cancer Progression -- Metabolic Perturbations Associated with Adipose Tissue Dysfunction and the Obesity-Cancer Link -- Increased Adiposity and Colorectal Cancer -- Adiposity and Diabetes in Breast and Prostate Cancer -- Increased Adipocity and Endometrial Cancer Risk -- Adipokines: Soluble Factors from Adipose Tissue Implicated in Cancer -- Animal Models to Study the Interplay between Cancer and Obesity -- Unraveling the local influence of tumor-surrounding adipose tissue on tumor progression: cellular and molecular actors involved -- Trafficking of Cells from Adipose Tissue to Tumor Microenvironment -- The Impact of Obesity Intervention on Cancer: Clinical Perspectives -- Index
Dimensions
unknown
Extent
1 online resource (193 p.)
Form of item
online
Isbn
9781461476603
Media category
computer
Media type code
c
Other control number
10.1007/978-1-4614-7660-3
Specific material designation
remote
System control number
  • (CKB)2670000000406485
  • (EBL)1398458
  • (SSID)ssj0000958030
  • (PQKBManifestationID)11516385
  • (PQKBTitleCode)TC0000958030
  • (PQKBWorkID)10985438
  • (PQKB)10646772
  • (DE-He213)978-1-4614-7660-3
  • (MiAaPQ)EBC1398458
  • (EXLCZ)992670000000406485
Label
Adipose Tissue and Cancer, edited by Mikhail G. Kolonin, (electronic resource)
Publication
Note
Description based upon print version of record
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
cr
Content category
text
Content type code
txt
Contents
Preface: Obesity, Adipose Tissue and Cancer Progression -- Metabolic Perturbations Associated with Adipose Tissue Dysfunction and the Obesity-Cancer Link -- Increased Adiposity and Colorectal Cancer -- Adiposity and Diabetes in Breast and Prostate Cancer -- Increased Adipocity and Endometrial Cancer Risk -- Adipokines: Soluble Factors from Adipose Tissue Implicated in Cancer -- Animal Models to Study the Interplay between Cancer and Obesity -- Unraveling the local influence of tumor-surrounding adipose tissue on tumor progression: cellular and molecular actors involved -- Trafficking of Cells from Adipose Tissue to Tumor Microenvironment -- The Impact of Obesity Intervention on Cancer: Clinical Perspectives -- Index
Dimensions
unknown
Extent
1 online resource (193 p.)
Form of item
online
Isbn
9781461476603
Media category
computer
Media type code
c
Other control number
10.1007/978-1-4614-7660-3
Specific material designation
remote
System control number
  • (CKB)2670000000406485
  • (EBL)1398458
  • (SSID)ssj0000958030
  • (PQKBManifestationID)11516385
  • (PQKBTitleCode)TC0000958030
  • (PQKBWorkID)10985438
  • (PQKB)10646772
  • (DE-He213)978-1-4614-7660-3
  • (MiAaPQ)EBC1398458
  • (EXLCZ)992670000000406485

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