The Resource Administration of naloxone in a home or community setting : a review of the clinical effectiveness, cost-effectiveness, and guidelines, prepared by Canadian Agency for Drugs and Technologies in Health, (electronic resource)

Administration of naloxone in a home or community setting : a review of the clinical effectiveness, cost-effectiveness, and guidelines, prepared by Canadian Agency for Drugs and Technologies in Health, (electronic resource)

Label
Administration of naloxone in a home or community setting : a review of the clinical effectiveness, cost-effectiveness, and guidelines
Title
Administration of naloxone in a home or community setting
Title remainder
a review of the clinical effectiveness, cost-effectiveness, and guidelines
Statement of responsibility
prepared by Canadian Agency for Drugs and Technologies in Health
Contributor
Issuing body
Subject
Language
  • eng
  • eng
Summary
Natural or synthetic opioids can be used therapeutically, recreationally, and children may be unintentionally exposed to them. Opioid addiction and abuse is a major medical and social problem all around the world. The opioids exert their biologic effects through interactions with multiple opioid receptors (, and ). The -opioid receptor is attributed to respiratory depression - a main hazard of severe opioid overdose which is potentially fatal. Opioid antagonists are commonly used as rescue medications to reverse severe opioid-induced respiratory depression. Naloxone is a non-selective, short-acting opioid receptor antagonist which acts on the -, - and -opioid receptors. It has been approved by Health Canada as an opioid antagonist since 1994. The most common use of naloxone is for the treatment of opioid overdose in both hospital and out-patient settings, and in rapid detoxification (being given intravenously [i.v.] when combined with other medications). Other routes of administration include intramuscular, subcutaneous, intranasal and through an endotracheal tube. The administration of naloxone in a home or community setting for overdose prevention may be an attractive option to reduce over-dose related deaths as it appears to be feasible and safe. In Canada, there are at least four cities with local overdose prevention and response programs involving naloxone dispensing, while British Columbia has recently launched a provincial program. Currently in Ontario, naloxone is not listed on the formulary or available through the province's Exceptional Access Program. The purpose of this review is to assess the evidence of the clinical effectiveness and cost-effectiveness of the administration of naloxone in a community or home setting versus naloxone administered by a health professional. Evidence-based guidelines and recommendations for the dosing of naloxone in this setting will also be discussed
Member of
Illustrations
illustrations
Index
no index present
Literary form
non fiction
Nature of contents
surveys of literature
http://library.link/vocab/relatedWorkOrContributorName
Canadian Agency for Drugs and Technologies in Health
Series statement
  • Rapid response report: summary with critical appraisal
  • NCBI Bookshelf
http://library.link/vocab/subjectName
  • Naloxone
  • Self Medication
  • Drug Prescriptions
  • Drug Administration Routes
  • Comparative Effectiveness Research
  • Guidelines as Topic
  • Canada
Label
Administration of naloxone in a home or community setting : a review of the clinical effectiveness, cost-effectiveness, and guidelines, prepared by Canadian Agency for Drugs and Technologies in Health, (electronic resource)
Instantiates
Publication
Note
  • Title from PDF caption title
  • Description based on version viewed March 16, 2015
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Extent
1 online resource (1 PDF file (17 pages))
Form of item
electronic
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations.
System control number
  • (CKB)3710000000379846
  • (EXLCZ)993710000000379846
Label
Administration of naloxone in a home or community setting : a review of the clinical effectiveness, cost-effectiveness, and guidelines, prepared by Canadian Agency for Drugs and Technologies in Health, (electronic resource)
Publication
Note
  • Title from PDF caption title
  • Description based on version viewed March 16, 2015
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Extent
1 online resource (1 PDF file (17 pages))
Form of item
electronic
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations.
System control number
  • (CKB)3710000000379846
  • (EXLCZ)993710000000379846

Library Locations

  • Albert D. Cohen Management LibraryBorrow it
    181 Freedman Crescent, Winnipeg, MB, R3T 5V4, CA
    49.807878 -97.129961
  • Architecture/Fine Arts LibraryBorrow it
    84 Curry Place, Winnipeg, MB, CA
    49.807716 -97.136226
  • Archives and Special CollectionsBorrow it
    25 Chancellors Circle (Elizabeth Dafoe Library), Room 330, Winnipeg, MB, R3T 2N2, CA
    49.809961 -97.131878
  • Bibliothèque Alfred-Monnin (Université de Saint-Boniface)Borrow it
    200, avenue de la Cathédrale, Local 2110, Winnipeg, MB, R2H 0H7, CA
    49.888861 -97.119735
  • Bill Larson Library (Grace Hospital)Borrow it
    300 Booth Drive, G-227, Winnipeg, MB, R3J 3M7, CA
    49.882400 -97.276436
  • Carolyn Sifton - Helene Fuld Library (St. Boniface General Hospital)Borrow it
    409 Tache Avenue, Winnipeg, MB, R2H 2A6, CA
    49.883388 -97.126050
  • Concordia Hospital LibraryBorrow it
    1095 Concordia Avenue, Winnipeg, MB, R2K 3S8, CA
    49.913252 -97.064683
  • Donald W. Craik Engineering LibraryBorrow it
    75B Chancellors Circle (Engineering Building E3), Room 361, Winnipeg, MB, R3T 2N2, CA
    49.809053 -97.133292
  • E.K. Williams Law LibraryBorrow it
    224 Dysart Road, Winnipeg, MB, R3T 5V4, CA
    49.811829 -97.131017
  • Eckhardt-Gramatté Music LibraryBorrow it
    136 Dafoe Road (Taché Arts Complex), Room 257, Winnipeg, MB, R3T 2N2, CA
    49.807964 -97.132222
  • Elizabeth Dafoe LibraryBorrow it
    25 Chancellors Circle, Winnipeg, MB, R3T 2N2, CA
    49.809961 -97.131878
  • Fr. H. Drake Library (St. Paul's College)Borrow it
    70 Dysart Road, Winnipeg, MB, R3T 2M6, CA
    49.810605 -97.138184
  • J.W. Crane Memorial Library (Deer Lodge Centre)Borrow it
    2109 Portage Avenue, Winnipeg, MB, R3J 0L3, CA
    49.878000 -97.235520
  • Libraries Annex (not open to the public; please see web page for details)Borrow it
    25 Chancellors Circle (in the Elizabeth Dafoe Library), Winnipeg, MB, R3T 2N2, CA
    49.809961 -97.131878
  • Neil John Maclean Health Sciences LibraryBorrow it
    727 McDermot Avenue (Brodie Centre), 200 Level, Winnipeg, MB, R3E 3P5, CA
    49.903563 -97.160554
  • Sciences and Technology LibraryBorrow it
    186 Dysart Road, Winnipeg, MB, R3T 2M8, CA
    49.811526 -97.133257
  • Seven Oaks General Hospital LibraryBorrow it
    2300 McPhillips Street, Winnipeg, MB, R2V 3M3, CA
    49.955177 -97.148865
  • Sister St. Odilon Library (Misericordia Health Centre)Borrow it
    99 Cornish Avenue, Winnipeg, MB, R3C 1A2, CA
    49.879592 -97.160425
  • St. John's College LibraryBorrow it
    92 Dysart Road, Winnipeg, MB, R3T 2M5, CA
    49.811242 -97.137156
  • Victoria General Hospital LibraryBorrow it
    2340 Pembina Highway, Winnipeg, MB, R3T 2E8, CA
    49.806755 -97.152739
  • William R Newman Library (Agriculture)Borrow it
    66 Dafoe Road, Winnipeg, MB, R3T 2R3, CA
    49.806936 -97.135525
Processing Feedback ...