The Resource Applications of Toxicogenomics in Safety Evaluation and Risk Assessment, (electronic resource)

Applications of Toxicogenomics in Safety Evaluation and Risk Assessment, (electronic resource)

Label
Applications of Toxicogenomics in Safety Evaluation and Risk Assessment
Title
Applications of Toxicogenomics in Safety Evaluation and Risk Assessment
Creator
Contributor
Subject
Genre
Language
  • eng
  • eng
Summary
This book provides a timely overview of toxicogenomics, with special emphasis on the practical applications of this technology to the risk assessment process. Introductory sections are followed by a series of chapters highlighting practical and systematic applications of toxicogenomics in informing the risk assessment process - including the areas of mutagenicity, carcinogenicity, endocrine toxicity, organ-specific toxicity, population monitoring, and ecotoxicology. The book concludes with approaches for the integration of this technology in safety evaluation studies, and an outlook on how tox
Cataloging source
AU-PeEL
http://library.link/vocab/creatorName
Boverhof, Darrell R
Dewey number
  • 616.042
  • 616/.042
Language note
English
LC call number
RA1224.3.B68 2011
Nature of contents
dictionaries
http://library.link/vocab/relatedWorkOrContributorName
Gollapudi, B. Bhaskar
http://library.link/vocab/subjectName
  • Genetic toxicology
  • Genetic toxicology
  • Health risk assessment
  • Health risk assessment
  • Risk Assessment
  • Toxicity testing
  • Toxicity testing
  • Toxicogenetics
  • Genetic toxicology
  • Toxicity testing
  • Health risk assessment
  • Toxicology
  • Pharmacogenetics
  • Risk
  • Risk Management
  • Epidemiologic Measurements
  • Organization and Administration
  • Pharmacology
  • Probability
  • Genetics
  • Public Health
  • Health Occupations
  • Statistics as Topic
  • Biological Science Disciplines
  • Biology
  • Health Services Administration
  • Environment and Public Health
  • Disciplines and Occupations
  • Natural Science Disciplines
  • Health Care
  • Health Care Evaluation Mechanisms
  • Epidemiologic Methods
  • Quality of Health Care
  • Investigative Techniques
  • Health Care Quality, Access, and Evaluation
  • Analytical, Diagnostic and Therapeutic Techniques and Equipment
  • Risk Assessment
  • Toxicogenetics
  • Public Health
  • Health & Biological Sciences
  • Toxicology & Public Health
Label
Applications of Toxicogenomics in Safety Evaluation and Risk Assessment, (electronic resource)
Instantiates
Publication
Note
Description based upon print version of record
Carrier category
online resource
Carrier category code
cr
Content category
text
Content type code
txt
Contents
  • Contents; Preface; Contributors; 1 Toxicology, ""Omics"" Technologies, and Toxicogenomics: A Primer; 2 Introduction to Human Health Risk Assessment; 3 Practical Considerations for the Application of Toxicogenomics to Risk Assessment: Early Experience, Current Drivers, and a Path Forward; 4 Approaches and Practical Considerations for the Analysis of Toxicogenomics Data; 5 Genomics in Identifying Mutagenic Mode of Action in Carcinogenesis; 6 Application of Genomics for Predicting and Understanding the Mode of Action for Nongenotoxic Carcinogens; 7 Genomics in Characterizing Endocrine Toxicity
  • 8 Studying Organ-Specific Toxicity Using Gene-Expression Profiling9 Toxicogenomic Studies in Human Populations; 10 Toxicogenomics Applied to Ecological Risk Assessment; 11 Analysis of Transcriptomic Dose-Response Data for Toxicology and Risk Assessment; 12 Toxicogenomics as a Tool for Validating Animal to Human Extrapolations in Chemical Risk Assessment: Concepts, Applications, and Challenges; 13 Toxicogenomics and Animal Alternatives; 14 Toxicogenomics and the Regulatory Framework; 15 Standardization of Gene-Expression Information for the Safety Evaluation: Activities in Japan
  • 16 Applying Transcriptional Profiling in Drug Safety Evaluation17 Reframing the Risk Assessment Paradigm: Toward a Systems Biology Approach; Index
Dimensions
unknown
Extent
1 online resource (402 p.)
Form of item
electronic
Isbn
9786613239662
Media category
computer
Media type code
c
Specific material designation
remote
System control number
  • (CKB)2550000000045637
  • (EBL)693202
  • (OCoLC)746321023
  • (SSID)ssj0000534058
  • (PQKBManifestationID)12215780
  • (PQKBTitleCode)TC0000534058
  • (PQKBWorkID)10510847
  • (PQKB)11321286
  • (EXLCZ)992550000000045637
Label
Applications of Toxicogenomics in Safety Evaluation and Risk Assessment, (electronic resource)
Publication
Note
Description based upon print version of record
Carrier category
online resource
Carrier category code
cr
Content category
text
Content type code
txt
Contents
  • Contents; Preface; Contributors; 1 Toxicology, ""Omics"" Technologies, and Toxicogenomics: A Primer; 2 Introduction to Human Health Risk Assessment; 3 Practical Considerations for the Application of Toxicogenomics to Risk Assessment: Early Experience, Current Drivers, and a Path Forward; 4 Approaches and Practical Considerations for the Analysis of Toxicogenomics Data; 5 Genomics in Identifying Mutagenic Mode of Action in Carcinogenesis; 6 Application of Genomics for Predicting and Understanding the Mode of Action for Nongenotoxic Carcinogens; 7 Genomics in Characterizing Endocrine Toxicity
  • 8 Studying Organ-Specific Toxicity Using Gene-Expression Profiling9 Toxicogenomic Studies in Human Populations; 10 Toxicogenomics Applied to Ecological Risk Assessment; 11 Analysis of Transcriptomic Dose-Response Data for Toxicology and Risk Assessment; 12 Toxicogenomics as a Tool for Validating Animal to Human Extrapolations in Chemical Risk Assessment: Concepts, Applications, and Challenges; 13 Toxicogenomics and Animal Alternatives; 14 Toxicogenomics and the Regulatory Framework; 15 Standardization of Gene-Expression Information for the Safety Evaluation: Activities in Japan
  • 16 Applying Transcriptional Profiling in Drug Safety Evaluation17 Reframing the Risk Assessment Paradigm: Toward a Systems Biology Approach; Index
Dimensions
unknown
Extent
1 online resource (402 p.)
Form of item
electronic
Isbn
9786613239662
Media category
computer
Media type code
c
Specific material designation
remote
System control number
  • (CKB)2550000000045637
  • (EBL)693202
  • (OCoLC)746321023
  • (SSID)ssj0000534058
  • (PQKBManifestationID)12215780
  • (PQKBTitleCode)TC0000534058
  • (PQKBWorkID)10510847
  • (PQKB)11321286
  • (EXLCZ)992550000000045637

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