The Resource Biochemical, physiological, and molecular aspects of human nutrition, [edited by] Martha H. Stipanuk, Marie A. Caudill

Biochemical, physiological, and molecular aspects of human nutrition, [edited by] Martha H. Stipanuk, Marie A. Caudill

Label
Biochemical, physiological, and molecular aspects of human nutrition
Title
Biochemical, physiological, and molecular aspects of human nutrition
Statement of responsibility
[edited by] Martha H. Stipanuk, Marie A. Caudill
Contributor
Subject
Language
eng
Cataloging source
DNLM/DLC
Dewey number
612.3/9
Illustrations
illustrations
Index
index present
LC call number
QP141
LC item number
.B57 2013
Literary form
non fiction
Nature of contents
bibliography
NLM call number
QU 145
http://library.link/vocab/relatedWorkOrContributorName
  • Stipanuk, Martha H
  • Caudill, Marie A
http://library.link/vocab/subjectName
  • Nutrition
  • Metabolism
  • Biochemistry
  • Nutritional Physiological Phenomena
  • Metabolism
Label
Biochemical, physiological, and molecular aspects of human nutrition, [edited by] Martha H. Stipanuk, Marie A. Caudill
Instantiates
Publication
Bibliography note
Includes bibliographical references and index
Contents
  • Concerns about Excessive Intakes
  • Factors Affecting Formation and Secretion of Chylomicrons
  • Portal Transport of Long-Chain Fatty Adds
  • Hormonal Regulation of lipid Absorption
  • Disorders of Intestinal Lipid Absorption
  • Intestinal Fatty Acids and Mucosal Injury
  • Satiety Effects of Fat Feeding
  • 11.
  • Dietary Fiber
  • Joanne L. Slavin
  • Definition of Fiber
  • Nutrients That Do Not Meet the Strict Criteria for Essentiality
  • Chemical and Physical Characterization of Dietary Fiber
  • Physiological Characterization of Dietary Fiber
  • Major Physiological Effects of Fiber and Structure-Function Relationships
  • Effects of Fiber on Whole-Body Energy Statue
  • Recommendations for Fiber Intake and Typical Intakes
  • Dietary Fiber Intake and Disease
  • Dietary Fiber and Microbiota
  • Unit IV
  • Metabolism of the Macronutrients
  • 12.
  • Health Effects of Nutrients and Nonnutrient Components of Food
  • Carbohydrate Metabolism: Synthesis and Oxidation
  • Mary M. McGrane
  • Overview of Tissue-Specific Glucose Metabolism
  • Transport of Glucose across Cell Membranes
  • Glycolysis
  • Metabolism of Monosaccharides Other Than Glucose
  • Gluconeogenesis
  • Regulation of Glycolysis and Glycogen Metabolism
  • Pyruvate Dehydrogenase Complex and Citric Acid Cycle
  • Electron Transport and Oxidative Phosphorylation
  • Use of Nutrients as Pharmacological Agents
  • ATP Equivalents Produced from the Complete Oxidation of Glucose
  • Other Pathways of Carbohydrate Metabolism
  • Dietary Reference Intakes and Typical Intakes of Carbohydrates
  • 13.
  • Protein Synthesis and Degradation
  • Margaret McNurlan
  • Protein Turnover
  • Protein Synthesis
  • Molecular Mechanisms of Protein Degradation
  • Role of Hormones and Cytokines in Regulation of Protein Turnover
  • 2.
  • Responses of Protein Turnover to Nutrient Supply
  • Protein Turnover in Growth and Exercise
  • Protein Loss with Disuse, Injury, and Disease
  • Current Challenges in Protein Metabolism
  • 14.
  • Amino Acid Metabolism
  • John T. Brosnan
  • Overview of Amino Acid Metabolism
  • Amino Acid Pools and Transport
  • Amino Acids as Signaling Agents
  • Food Components with Health Benefits
  • Two Themes in Amino Acid Metabolism
  • Synthesis of Dispensable Amino Acids
  • Interorgan Amino Acid Metabolism
  • Metabolism of the Dispensable Amino Acids
  • Catabolism of Indispensable Amino Acids
  • Neuroactive Amines, Hormones, and Pigments Formed from Amino Acids by Specialized Cell Types
  • Nitrogen Excretion
  • 15.
  • Protein and Amino Acid Requirements
  • Ronald O. Ball
  • Anna-Sigrid Keck
  • Classification of Dispensable and Indispensable Amino Acids
  • Requirement for Protein (Amino Acids)
  • Requirements for Individual Amino Acids
  • Factors That Affect Amino Acid Requirements
  • Food Proteins and Protein Quality
  • Typical Intakes of Protein and Amino Acids and Significance of Protein to Energy Ratios
  • Effects of Inadequate Protein Intake and Assessment of Protein Status
  • How Much Protein is Too Much Protein?
  • Need for Additional Research in Nutritional Science
  • 16.
  • Functional Foods and Dietary Supplements
  • Metabolism of Fatty Acids, Acylglycerols, and Sphingolipids
  • Hei Sook Sul
  • Biological Roles for Lipids
  • Overview of Fatty Acid and Triacylglycerol Metabolism
  • Synthesis of Palmitate from Acetyl-CoA
  • Transfer of Acetyl-CoA from Inside the Mitochondria to the Cytosol
  • Synthesis of Fatty Acids Other Than Palmitate
  • Synthesis of Triacylglycerol
  • Hydrolysis of Triacylglycerol in Lipoproteins, Uptake of Fatty Acids, and Utilization of Fatty Acids for Energy or Storage as Triacylglycerol
  • Mobilization of Stored Triacylglycerol
  • Carotenoids
  • Oxidation of Fatty Acids
  • β-Oxidation of Fatty Acids with an Odd Number of Carbons or with Methyl Side Chains to Generate Propionyl-CoA
  • Formation of Ketone Bodies from Acetyl-CoA in the Liver as a Fuel for Extrahepatic Tissues
  • Phosphatidic Acid and Diacylglycerol as Precursors of the Common Phospholipids
  • Remodeling of Phospholipids in Situ
  • Generation of Signaling Molecules by Regulated Phospholipases
  • Synthesis of Ether-Linked Glycerolphospholipids
  • 17.
  • Cholesterol and Lipoproteins: Synthesis, Transport, and Metabolism
  • Judith Storch
  • Polyunsaturated Fatty Acids
  • Overview of Cholesterol Metabolism
  • Synthesis of Cholesterol and Isoprenoids
  • Regulation of Cholesterol Synthesis
  • Intracellular Trafficking of Cholesterol Synthesized in Cell versus Cholesterol Taken from Plasma in LDL
  • Synthesis of Steroid Hormones from Cholesterol
  • Synthesis of Bile Acids and Oxysterols from Cholesterol
  • Cholesterol Transport During Enterohepatic Recirculation
  • Lipoproteins and Their Metabolism
  • Postprandial Lipoprotein Metabolism
  • Atherosclerotic Cardiovascular Disease
  • Machine generated contents note:
  • Plant Sterols/Stanols
  • Chronic Effects of Dietary Lipids on Plasma Lipoproteins and Lipid Metabolism
  • Recommendations and Typical Intakes for Dietary Fat
  • 18.
  • Lipid Metabolism: Polyunsaturated Fatty Acids
  • Richard P. Bazinet
  • Discovery of Essential Fatty Acids
  • Structure of Polyunsaturated Fatty Acids
  • Essential Fatty Acid Metabolism
  • Essential Fatty Acid Composition of Plasma and Tissue Lipids
  • Functions of Polyunsaturated Fatty Acids
  • Polyphenolics
  • Regulation of Gene Expression by Essential Fatty Acids
  • Recommendations for Essential Fatty Acid Intake
  • Essential Fatty Acid Deficiency
  • Peroxidation of Polyunsaturated Fatty Acids
  • 19.
  • Regulation of Fuel Utilization in Response to Food Intake
  • Martha H. Stipanuk
  • Regulation of Macronutrient Metabolism at the Whole-Body Level
  • Distributed Control
  • Regulation of Macronutrient Metabolism at the Cellular Level
  • Phytoestrogens
  • Integrative Pathways for Regulation of Macronutrient Metabolism at the Cellular Level
  • Metabolic Fates of Macronutrients
  • Stages of Glucose Homeostasis during Prolonged Starvation
  • 20.
  • Regulation of Fuel Utilization in Response to Physical Activity
  • Martha H. Stipanuk
  • Muscle Structure
  • Muscle Fiber Types
  • Energy Cost of Movement
  • Skeletal Muscle Fuel Utilization During Rest
  • Isothiocyanates
  • Fuel Utilization by Working Muscle
  • Fuels for Short Bursts of Super Intense Physical Activity
  • Skeletal Muscle Adaptations in Response to Training and the Consequences for Fuel Utilization and Performance
  • Nutritional and Ergogenic Aids to Training and/or Performance
  • Muscle Fuel Utilization and Health Outcomes
  • Skeletal Muscle Adaptations in Response to Disuse, Aging, and Disease and the Consequences for Fuel Utilization and Well-Being During Normal Daily Life
  • Unit V
  • Energy --
  • Organosulfurs
  • Polyols
  • Dietary Fiber
  • Prebiotics/Probiotics
  • Overall Recommendations
  • 3.
  • Unit I
  • Guidelines for Food and Nutrient Intake
  • Christina Stark
  • Dietary Reference Intakes
  • Dietary Advice: Goals and Guidelines
  • Food Guides
  • Labeling of Foods and Supplements
  • Unit II
  • Structure and Properties of Micronutrients
  • 4.
  • Structure, Nomenclature, and Properties of Carbohydrates
  • Nutrients: Essential and Nonessential
  • Joanne L. Slavin
  • Monosaccharides or Sugar Residues
  • Other Classes of Carbohydrate Units
  • Disaccharides and Oligosaccharides and Their Properties
  • Polysaccharides of Nutritional Importance
  • Glycoconjugates of Physiological Interest
  • 5.
  • Structure, Nomenclature, and Properties of Proteins and Amino Acids
  • Martha H. Stipanuk
  • Proteinogenic Amino Acids
  • 1.
  • Modifications of Amino Acid Side Chains
  • Synthesis of Peptides and Proteins
  • Protein Structure
  • Stabilization of Protein Conformations
  • Stable Posttranslational Modifications of Proteins
  • Regulation of the Amount of Protein and Its Functional State
  • 6.
  • Structure, Nomenclature, and Properties of Lipids
  • Gavin L. Sacks
  • Chemical Classes of Lipids---Their Structure and Nomenclature
  • Nutrients: History and Definitions
  • Fatty Acids and Food Fats
  • Physical and Structural Properties of Lipids
  • Unit III
  • Digestion and Absorption of the Macronutrients
  • 7.
  • Overview of Digestion and Absorption
  • Patrick Tso
  • General Structure and Function of the GI Tract
  • Upper GI System
  • Small Intestine
  • Martha H. Stipanuk
  • Large Intestine
  • 8.
  • Digestion and Absorption of Carbohydrate
  • Edith Brot-Laroche
  • Carbohydrate Components of the Human Diet
  • Digestion of Starch
  • Digestion of Dietary Disaccharides
  • Expression and Processing of the Oligosaccharidases and Disaccharidases
  • Glycosidic Bonds Not Hydrolyzed by Human Digestive Enzymes
  • Absorption of Monosaccharides by the Enterocyte
  • Discovery of the Nutrients
  • Factors Affecting Carbohydrate Assimilation
  • Deficiencies of Carbohydrate Assimilation
  • 9.
  • Digestion and Absorption of Protein
  • Bruce R. Stevens
  • Digestion of Protein in the Gastrointestinal Tract
  • Gastric Phase: Denaturation and Initial Hydrolysis of Proteins
  • Small Intestinal Luminal Phase: Activation and Action of Pancreatic Proteolytic Enzymes
  • Small Intestinal Mucosal Phase: Brush Border and Cytosolic Peptidases
  • Absorption of Free Amino Adds and Small Peptides
  • Setting Criteria for Essentiality
  • Metabolism of Amino Adds in Intestinal Epithelial Cells
  • Use of Free Amino Adds and Peptides for Oral Rehydration Therapy
  • Physiologically Active Dietary Peptides
  • Determining Dietary Protein Digestibility
  • 10.
  • Digestion and Absorption of Lipids
  • Ronald J. Jandacek
  • Luminal Digestion of Lipids
  • Uptake of Lipid Digestion Products by the Enterocytes
  • Intracellular Metabolism of Absorbed Lipids
  • Edward O. List
  • Metabolism, Turnover, and Transport of Vitamin B6
  • Metabolic Functions of Vitamin B6
  • Vitamin B6 Deficiency: Symptoms and Metabolic Bases
  • Vitamin B6 and Disease Risk
  • Detection of Vitamin B6 Deficiency
  • Vitamin B6 Requirements
  • Vitamin B6 Intake
  • Vitamin B6 Toxicity
  • 26.
  • Biotin and Pantothenic Acid
  • Energy Balance
  • Neil I. Matthews
  • Biotin
  • Biotin Synthesis
  • Holocarboxylases and Holocarboxylase Synthetase
  • Biotin-Containing Carboxylases
  • Biotin and Gene Regulation
  • Biotin Digestion and Absorption
  • Biotin Uptake and Transport in Tissues
  • Biotin Degradation
  • Biotin Deficiency
  • Nutrient Balance
  • Inborn Errors of Biotin Metabolism
  • Dietary Sources and Recommended Intakes
  • Toxicity
  • Pantothenic Acid
  • Pantothenic Acid Synthesis
  • Dietary Sources and Intake
  • Digestion, Absorption, and Transport
  • Metabolism of Pantothenic Acid to CoA and ACP
  • Functions of CoA and ACP
  • CoA and Carnitine
  • Relative Stability of Body Weight
  • Dietary Requirement
  • Pantothenic Acid Deficiency
  • Purported Therapeutic Uses of Pantothenic Acid
  • Toxicity
  • 27.
  • Vitamin C
  • Balz Frei
  • Vitamin C Nomenclature, Structure, and Chemical Properties
  • Ascorbate
  • Food Sources of Vitamin C
  • Behavioral Aspects of Control of Energy Intake and Energy Expenditure
  • Vitamin C Transport
  • Enzymatic Functions of Vitamin C
  • Nonenzymatic Functions of Vitamin C
  • Vitamin C and Human Health
  • Dietary Reference Intakes for Vitamin C
  • 28.
  • Vitamin K
  • Reidar Wallin
  • Nomenclature of Vitamin K Active Compounds
  • Mechanism of Action of Vitamin K
  • Biological Control of Energy Intake and Energy Expenditure
  • Antagonism of Vitamin K Action by Clinically Used Inhibitors
  • Warfarin Resistance and the Vitamin K-Dependent γ-Carboxylation System
  • Sources of Vitamin K
  • Vitamin K1 Conversion to MK-4 in Extrahepatic Tissues
  • Bioavailability
  • Absorption, Transport, and Metabolism of Vitamin K
  • Physiological Roles of Vitamin K-Dependent Proteins
  • Vitamin K Deficiency
  • Assessment of Vitamin K Status
  • Recommendations for Vitamin K Intake
  • Afferent Signals
  • 29.
  • Vitamin E
  • Robert S. Parker
  • Nomenclature and Structure of Vitamin E
  • Absorption, Transport, and Metabolism of Vitamin E
  • Biological Functions of Vitamin E
  • Deficiency, Health Effects, and Biopotency of Vitamin E
  • Food Sources and Intake of Vitamin E
  • Recommended Intake of Vitamin E and Assessment of Vitamin E Status
  • 30.
  • Central Nervous System Integration of Satiety and Adiposity Signals
  • Vitamin A
  • Noa Noy
  • Chemistry and Physical Properties of Vitamin A and Carotenoids
  • Physiological Functions of Vitamin A
  • Absorption, Transport, Storage, and Metabolism of Vitamin A and Carotenoids
  • Retinol-Binding Proteins
  • Nutritional Considerations of Vitamin A
  • 31.
  • Vitamin D
  • Steven K. Clinton
  • Efferent Signals
  • Dietary and Endogenous Sources of Vitamin D
  • Biological Actions of Vitamin D
  • Evaluation of Vitamin D Status
  • Dietary Sources of Vitamin D
  • Solar Contribution to Vitamin D Status
  • Vitamin D Toxicity
  • Dietary Reference Intakes for Vitamin D
  • Vitamin D and Health Outcomes
  • Controversy Over Recommendations for Vitamin D Intake and Status Testing
  • Unit VII
  • Importance of Diet and Exercise in Prevention of Overweight and Obesity
  • Minerals and Water
  • 32.
  • Calcium and Phosphorus
  • Sue A. Shapses
  • Chemical Properties of Calcium
  • Chemical Properties of Phosphate
  • Physiological and Metabolic Functions of Calcium and Phosphate
  • Hormonal Regulation of Calcium and Phosphate Metabolism
  • Calcium and Phosphate Homeostasis
  • Dietary Sources, Bioavailability, and Recommended Intakes for Calcium and Phosphorus
  • Contents note continued:
  • 23.
  • Calcium and Phosphate Deficiency, Excess, and Assessment of Status
  • Clinical Disorders Involving Altered Calcium and Phosphate Levels
  • 33.
  • Magnesium
  • Jurgen Vormann
  • Chemistry of Magnesium
  • Absorption, Bioavailability, and Excretion of Magnesium
  • Body Magnesium Content
  • Physiological Roles of Magnesium
  • Food Sources, Recommended Intakes, and Dietary Intakes of Magnesium
  • Disturbances of Energy Balance
  • Magnesium Depletion
  • Diagnosis of Magnesium Deficiency
  • Magnesium Toxicity
  • Magnesium and Disease Risks
  • Conclusion
  • 34.
  • Sodium, Chloride, and Potassium
  • Hwai-Ping Sheng
  • Functions and Distribution of Sodium, Chloride, and Potassium
  • Sodium, Chloride, and Potassium Balance
  • Christopher A. Taylor
  • Regulation of Sodium, Chloride, and Potassium Balance
  • Interactions Among Systems in Volume Regulation
  • Sodium and Chloride Imbalance and Its Consequences
  • Potassium Imbalance and Its Consequences
  • Nutritional Considerations
  • 35.
  • Body Fluids and Water Balance
  • Hwai-Ping Sheng
  • Physiological Functions of Water
  • Body Water Compartments
  • Adipose Tissue in Energy Balance
  • Water Balance
  • Renal Excretion of Water
  • Regulation of Water Balance
  • Water Imbalance and Its Consequences
  • 36.
  • Iron
  • Robert R. Crichton
  • Biological Functions of Iron
  • Proteins of Iron Transport, Storage, and Recycling
  • Body Iron Compartments and Daily Iron Exchange
  • Obesity
  • Internal Iron Exchange and Cellular Iron Metabolism
  • External Iron Exchange, Iron Absorption, and Systemic Iron Homeostasis
  • Dietary Reference Intakes for Iron
  • Iron Deficiency
  • Iron Excess
  • 37.
  • Zinc, Copper, and Manganese in Enzyme Systems
  • Arthur Grider
  • Absorption
  • Selected Functions of Zinc, Copper, and Manganese
  • Lipodystrophy
  • Assessment of Zinc, Copper, and Manganese Status and Deficiency Symptoms
  • Dietary Reference Intakes and Food Sources of Zinc, Copper, and Manganese
  • Toxicity of Zinc, Copper, and Manganese
  • 38.
  • Iodine
  • Hedley C. Freake
  • Production and Metabolism of Thyroid Hormones
  • Mechanism of Action of Thyroid Hormones
  • Physiological Functions of Thyroid Hormones
  • Iodine Deficiency
  • Starvation and Protein-Energy Malnutrition
  • Dietary Recommendations, Dietary Intake, and Toxicity
  • 39.
  • Selenium
  • Gerald F. Combs
  • Chemistry of Selenium
  • Utilization of Dietary Selenium
  • Selenoproteins
  • Tissue Distribution of Selenium
  • Nutritional Essentiality of Selenium
  • Selenium Toxicity
  • Definitions of PEM
  • Selenium Anticarcinogenesis
  • Human Selenium Requirements
  • Selenium Intakes
  • 40.
  • Fluoride
  • Gary M. Whitford
  • Dental Fluorosis and Dental Caries
  • Fluoride Intake
  • Fluoride Physiology
  • Acute Fluoride Toxicity
  • Unit VI
  • Chronic Fluoride Toxicity
  • 41.
  • Molybdenum and Beneficial Bioactive Trace Elements
  • Forrest H. Nielsen
  • Definition of Ultratrace Elements
  • Molybdenum
  • Boron
  • Chromium
  • Silicon
  • Vitamins
  • 21.
  • 24.
  • Niacin, Riboflavin, and Thiamin
  • W. Todd Penberthy
  • Niacin
  • Niacin History
  • Niacin Nomenclature, Structure, and Biochemistry
  • Niacin Physiological Function
  • Proteins That Require Niacin
  • Niacin Sources, Chemical Stability, and ADMET
  • Biochemical Assessment of Niacin Nutriture, Dietary Requirements, and High-Dose Responses
  • Cellular and Whole-Animal Energetics
  • Riboflavin
  • Riboflavin History
  • Riboflavin Nomenclature, Structure, and Biochemistry
  • Riboflavin Physiological Function
  • Proteins That Require Riboflavin
  • Riboflavin Sources, Chemical Stability, and ADMET
  • Biochemical Assessment of Riboflavin Nutriture and Dietary Requirements
  • Thiamin
  • Thiamin History
  • Thiamin Nomenclature, Structure, and Biochemistry
  • Matthew W. Hulver
  • Thiamin Physiological Function
  • Proteins That Require Thiamin
  • Thiamin Sources, Chemical Stability, and ADMET
  • Biochemical Assessment of Thiamin Nutriture and Dietary Requirements
  • Interdependence of B3, B2, and B1
  • 25.
  • Folate, Choline, Vitamin B12, and Vitamin B6
  • Barry Shane
  • Folate
  • Chemistry of Folate
  • Cellular Energetics
  • Sources of Folate
  • Folate Absorption
  • Folate Bioavailability
  • Transport of Folate
  • Tissue Accumulation of Folate
  • Folate Turnover
  • Metabolic Functions of Folate
  • Folate Deficiency: Symptoms, Metabolic Bases, and Disease
  • Folate Status Assessment
  • Folate Dietary Recommendations
  • Whole-Animal Energetics
  • Folate Toxicity
  • Choline
  • Choline Chemistry
  • Food Sources of Choline
  • Choline Absorption
  • Choline Bioavailablity
  • Transport of Choline
  • Metabolism of Choline
  • Physiological Functions of Choline
  • Choline Deficiency
  • 22.
  • Choline and Disease
  • Choline Homeostasis
  • Status Assessment of Choline
  • Dietary Recommendations, Factors Affecting Dietary Requirements, and Dietary Choline Intake
  • Choline Toxicity
  • Vitamin B12
  • Chemistry of Vitamin B12
  • Sources of Vitamin B12
  • Absorption and Bioavailability of Vitamin B12
  • Plasma Transport, Tissue Uptake, and Turnover of Vitamin B12
  • Control of Energy Balance
  • Intracellular Metabolism and Metabolic Functions of Vitamin B12
  • Vitamin B12 Deficiency: Symptoms and Metabolic Bases
  • Vitamin B12 Requirements
  • Vitamin B12 Dietary Intakes
  • Vitamin B12 Toxicity
  • Vitamin B6
  • Chemistry of Vitamin B6
  • Sources of Vitamin B6
  • Absorption of Vitamin B6
  • Bioavailability of Vitamin B6
Dimensions
27 cm.
Edition
3rd ed.
Extent
xix, 948 p.
Isbn
9781437709599
Isbn Type
(pbk.)
Lccn
2011031519
Other physical details
ill.
System control number
  • (CaMWU)u2512081-01umb_inst
  • 2567971
  • (Sirsi) i9781437709599
  • (DNLM)101565397
  • (OCoLC)743275919
Label
Biochemical, physiological, and molecular aspects of human nutrition, [edited by] Martha H. Stipanuk, Marie A. Caudill
Publication
Bibliography note
Includes bibliographical references and index
Contents
  • Concerns about Excessive Intakes
  • Factors Affecting Formation and Secretion of Chylomicrons
  • Portal Transport of Long-Chain Fatty Adds
  • Hormonal Regulation of lipid Absorption
  • Disorders of Intestinal Lipid Absorption
  • Intestinal Fatty Acids and Mucosal Injury
  • Satiety Effects of Fat Feeding
  • 11.
  • Dietary Fiber
  • Joanne L. Slavin
  • Definition of Fiber
  • Nutrients That Do Not Meet the Strict Criteria for Essentiality
  • Chemical and Physical Characterization of Dietary Fiber
  • Physiological Characterization of Dietary Fiber
  • Major Physiological Effects of Fiber and Structure-Function Relationships
  • Effects of Fiber on Whole-Body Energy Statue
  • Recommendations for Fiber Intake and Typical Intakes
  • Dietary Fiber Intake and Disease
  • Dietary Fiber and Microbiota
  • Unit IV
  • Metabolism of the Macronutrients
  • 12.
  • Health Effects of Nutrients and Nonnutrient Components of Food
  • Carbohydrate Metabolism: Synthesis and Oxidation
  • Mary M. McGrane
  • Overview of Tissue-Specific Glucose Metabolism
  • Transport of Glucose across Cell Membranes
  • Glycolysis
  • Metabolism of Monosaccharides Other Than Glucose
  • Gluconeogenesis
  • Regulation of Glycolysis and Glycogen Metabolism
  • Pyruvate Dehydrogenase Complex and Citric Acid Cycle
  • Electron Transport and Oxidative Phosphorylation
  • Use of Nutrients as Pharmacological Agents
  • ATP Equivalents Produced from the Complete Oxidation of Glucose
  • Other Pathways of Carbohydrate Metabolism
  • Dietary Reference Intakes and Typical Intakes of Carbohydrates
  • 13.
  • Protein Synthesis and Degradation
  • Margaret McNurlan
  • Protein Turnover
  • Protein Synthesis
  • Molecular Mechanisms of Protein Degradation
  • Role of Hormones and Cytokines in Regulation of Protein Turnover
  • 2.
  • Responses of Protein Turnover to Nutrient Supply
  • Protein Turnover in Growth and Exercise
  • Protein Loss with Disuse, Injury, and Disease
  • Current Challenges in Protein Metabolism
  • 14.
  • Amino Acid Metabolism
  • John T. Brosnan
  • Overview of Amino Acid Metabolism
  • Amino Acid Pools and Transport
  • Amino Acids as Signaling Agents
  • Food Components with Health Benefits
  • Two Themes in Amino Acid Metabolism
  • Synthesis of Dispensable Amino Acids
  • Interorgan Amino Acid Metabolism
  • Metabolism of the Dispensable Amino Acids
  • Catabolism of Indispensable Amino Acids
  • Neuroactive Amines, Hormones, and Pigments Formed from Amino Acids by Specialized Cell Types
  • Nitrogen Excretion
  • 15.
  • Protein and Amino Acid Requirements
  • Ronald O. Ball
  • Anna-Sigrid Keck
  • Classification of Dispensable and Indispensable Amino Acids
  • Requirement for Protein (Amino Acids)
  • Requirements for Individual Amino Acids
  • Factors That Affect Amino Acid Requirements
  • Food Proteins and Protein Quality
  • Typical Intakes of Protein and Amino Acids and Significance of Protein to Energy Ratios
  • Effects of Inadequate Protein Intake and Assessment of Protein Status
  • How Much Protein is Too Much Protein?
  • Need for Additional Research in Nutritional Science
  • 16.
  • Functional Foods and Dietary Supplements
  • Metabolism of Fatty Acids, Acylglycerols, and Sphingolipids
  • Hei Sook Sul
  • Biological Roles for Lipids
  • Overview of Fatty Acid and Triacylglycerol Metabolism
  • Synthesis of Palmitate from Acetyl-CoA
  • Transfer of Acetyl-CoA from Inside the Mitochondria to the Cytosol
  • Synthesis of Fatty Acids Other Than Palmitate
  • Synthesis of Triacylglycerol
  • Hydrolysis of Triacylglycerol in Lipoproteins, Uptake of Fatty Acids, and Utilization of Fatty Acids for Energy or Storage as Triacylglycerol
  • Mobilization of Stored Triacylglycerol
  • Carotenoids
  • Oxidation of Fatty Acids
  • β-Oxidation of Fatty Acids with an Odd Number of Carbons or with Methyl Side Chains to Generate Propionyl-CoA
  • Formation of Ketone Bodies from Acetyl-CoA in the Liver as a Fuel for Extrahepatic Tissues
  • Phosphatidic Acid and Diacylglycerol as Precursors of the Common Phospholipids
  • Remodeling of Phospholipids in Situ
  • Generation of Signaling Molecules by Regulated Phospholipases
  • Synthesis of Ether-Linked Glycerolphospholipids
  • 17.
  • Cholesterol and Lipoproteins: Synthesis, Transport, and Metabolism
  • Judith Storch
  • Polyunsaturated Fatty Acids
  • Overview of Cholesterol Metabolism
  • Synthesis of Cholesterol and Isoprenoids
  • Regulation of Cholesterol Synthesis
  • Intracellular Trafficking of Cholesterol Synthesized in Cell versus Cholesterol Taken from Plasma in LDL
  • Synthesis of Steroid Hormones from Cholesterol
  • Synthesis of Bile Acids and Oxysterols from Cholesterol
  • Cholesterol Transport During Enterohepatic Recirculation
  • Lipoproteins and Their Metabolism
  • Postprandial Lipoprotein Metabolism
  • Atherosclerotic Cardiovascular Disease
  • Machine generated contents note:
  • Plant Sterols/Stanols
  • Chronic Effects of Dietary Lipids on Plasma Lipoproteins and Lipid Metabolism
  • Recommendations and Typical Intakes for Dietary Fat
  • 18.
  • Lipid Metabolism: Polyunsaturated Fatty Acids
  • Richard P. Bazinet
  • Discovery of Essential Fatty Acids
  • Structure of Polyunsaturated Fatty Acids
  • Essential Fatty Acid Metabolism
  • Essential Fatty Acid Composition of Plasma and Tissue Lipids
  • Functions of Polyunsaturated Fatty Acids
  • Polyphenolics
  • Regulation of Gene Expression by Essential Fatty Acids
  • Recommendations for Essential Fatty Acid Intake
  • Essential Fatty Acid Deficiency
  • Peroxidation of Polyunsaturated Fatty Acids
  • 19.
  • Regulation of Fuel Utilization in Response to Food Intake
  • Martha H. Stipanuk
  • Regulation of Macronutrient Metabolism at the Whole-Body Level
  • Distributed Control
  • Regulation of Macronutrient Metabolism at the Cellular Level
  • Phytoestrogens
  • Integrative Pathways for Regulation of Macronutrient Metabolism at the Cellular Level
  • Metabolic Fates of Macronutrients
  • Stages of Glucose Homeostasis during Prolonged Starvation
  • 20.
  • Regulation of Fuel Utilization in Response to Physical Activity
  • Martha H. Stipanuk
  • Muscle Structure
  • Muscle Fiber Types
  • Energy Cost of Movement
  • Skeletal Muscle Fuel Utilization During Rest
  • Isothiocyanates
  • Fuel Utilization by Working Muscle
  • Fuels for Short Bursts of Super Intense Physical Activity
  • Skeletal Muscle Adaptations in Response to Training and the Consequences for Fuel Utilization and Performance
  • Nutritional and Ergogenic Aids to Training and/or Performance
  • Muscle Fuel Utilization and Health Outcomes
  • Skeletal Muscle Adaptations in Response to Disuse, Aging, and Disease and the Consequences for Fuel Utilization and Well-Being During Normal Daily Life
  • Unit V
  • Energy --
  • Organosulfurs
  • Polyols
  • Dietary Fiber
  • Prebiotics/Probiotics
  • Overall Recommendations
  • 3.
  • Unit I
  • Guidelines for Food and Nutrient Intake
  • Christina Stark
  • Dietary Reference Intakes
  • Dietary Advice: Goals and Guidelines
  • Food Guides
  • Labeling of Foods and Supplements
  • Unit II
  • Structure and Properties of Micronutrients
  • 4.
  • Structure, Nomenclature, and Properties of Carbohydrates
  • Nutrients: Essential and Nonessential
  • Joanne L. Slavin
  • Monosaccharides or Sugar Residues
  • Other Classes of Carbohydrate Units
  • Disaccharides and Oligosaccharides and Their Properties
  • Polysaccharides of Nutritional Importance
  • Glycoconjugates of Physiological Interest
  • 5.
  • Structure, Nomenclature, and Properties of Proteins and Amino Acids
  • Martha H. Stipanuk
  • Proteinogenic Amino Acids
  • 1.
  • Modifications of Amino Acid Side Chains
  • Synthesis of Peptides and Proteins
  • Protein Structure
  • Stabilization of Protein Conformations
  • Stable Posttranslational Modifications of Proteins
  • Regulation of the Amount of Protein and Its Functional State
  • 6.
  • Structure, Nomenclature, and Properties of Lipids
  • Gavin L. Sacks
  • Chemical Classes of Lipids---Their Structure and Nomenclature
  • Nutrients: History and Definitions
  • Fatty Acids and Food Fats
  • Physical and Structural Properties of Lipids
  • Unit III
  • Digestion and Absorption of the Macronutrients
  • 7.
  • Overview of Digestion and Absorption
  • Patrick Tso
  • General Structure and Function of the GI Tract
  • Upper GI System
  • Small Intestine
  • Martha H. Stipanuk
  • Large Intestine
  • 8.
  • Digestion and Absorption of Carbohydrate
  • Edith Brot-Laroche
  • Carbohydrate Components of the Human Diet
  • Digestion of Starch
  • Digestion of Dietary Disaccharides
  • Expression and Processing of the Oligosaccharidases and Disaccharidases
  • Glycosidic Bonds Not Hydrolyzed by Human Digestive Enzymes
  • Absorption of Monosaccharides by the Enterocyte
  • Discovery of the Nutrients
  • Factors Affecting Carbohydrate Assimilation
  • Deficiencies of Carbohydrate Assimilation
  • 9.
  • Digestion and Absorption of Protein
  • Bruce R. Stevens
  • Digestion of Protein in the Gastrointestinal Tract
  • Gastric Phase: Denaturation and Initial Hydrolysis of Proteins
  • Small Intestinal Luminal Phase: Activation and Action of Pancreatic Proteolytic Enzymes
  • Small Intestinal Mucosal Phase: Brush Border and Cytosolic Peptidases
  • Absorption of Free Amino Adds and Small Peptides
  • Setting Criteria for Essentiality
  • Metabolism of Amino Adds in Intestinal Epithelial Cells
  • Use of Free Amino Adds and Peptides for Oral Rehydration Therapy
  • Physiologically Active Dietary Peptides
  • Determining Dietary Protein Digestibility
  • 10.
  • Digestion and Absorption of Lipids
  • Ronald J. Jandacek
  • Luminal Digestion of Lipids
  • Uptake of Lipid Digestion Products by the Enterocytes
  • Intracellular Metabolism of Absorbed Lipids
  • Edward O. List
  • Metabolism, Turnover, and Transport of Vitamin B6
  • Metabolic Functions of Vitamin B6
  • Vitamin B6 Deficiency: Symptoms and Metabolic Bases
  • Vitamin B6 and Disease Risk
  • Detection of Vitamin B6 Deficiency
  • Vitamin B6 Requirements
  • Vitamin B6 Intake
  • Vitamin B6 Toxicity
  • 26.
  • Biotin and Pantothenic Acid
  • Energy Balance
  • Neil I. Matthews
  • Biotin
  • Biotin Synthesis
  • Holocarboxylases and Holocarboxylase Synthetase
  • Biotin-Containing Carboxylases
  • Biotin and Gene Regulation
  • Biotin Digestion and Absorption
  • Biotin Uptake and Transport in Tissues
  • Biotin Degradation
  • Biotin Deficiency
  • Nutrient Balance
  • Inborn Errors of Biotin Metabolism
  • Dietary Sources and Recommended Intakes
  • Toxicity
  • Pantothenic Acid
  • Pantothenic Acid Synthesis
  • Dietary Sources and Intake
  • Digestion, Absorption, and Transport
  • Metabolism of Pantothenic Acid to CoA and ACP
  • Functions of CoA and ACP
  • CoA and Carnitine
  • Relative Stability of Body Weight
  • Dietary Requirement
  • Pantothenic Acid Deficiency
  • Purported Therapeutic Uses of Pantothenic Acid
  • Toxicity
  • 27.
  • Vitamin C
  • Balz Frei
  • Vitamin C Nomenclature, Structure, and Chemical Properties
  • Ascorbate
  • Food Sources of Vitamin C
  • Behavioral Aspects of Control of Energy Intake and Energy Expenditure
  • Vitamin C Transport
  • Enzymatic Functions of Vitamin C
  • Nonenzymatic Functions of Vitamin C
  • Vitamin C and Human Health
  • Dietary Reference Intakes for Vitamin C
  • 28.
  • Vitamin K
  • Reidar Wallin
  • Nomenclature of Vitamin K Active Compounds
  • Mechanism of Action of Vitamin K
  • Biological Control of Energy Intake and Energy Expenditure
  • Antagonism of Vitamin K Action by Clinically Used Inhibitors
  • Warfarin Resistance and the Vitamin K-Dependent γ-Carboxylation System
  • Sources of Vitamin K
  • Vitamin K1 Conversion to MK-4 in Extrahepatic Tissues
  • Bioavailability
  • Absorption, Transport, and Metabolism of Vitamin K
  • Physiological Roles of Vitamin K-Dependent Proteins
  • Vitamin K Deficiency
  • Assessment of Vitamin K Status
  • Recommendations for Vitamin K Intake
  • Afferent Signals
  • 29.
  • Vitamin E
  • Robert S. Parker
  • Nomenclature and Structure of Vitamin E
  • Absorption, Transport, and Metabolism of Vitamin E
  • Biological Functions of Vitamin E
  • Deficiency, Health Effects, and Biopotency of Vitamin E
  • Food Sources and Intake of Vitamin E
  • Recommended Intake of Vitamin E and Assessment of Vitamin E Status
  • 30.
  • Central Nervous System Integration of Satiety and Adiposity Signals
  • Vitamin A
  • Noa Noy
  • Chemistry and Physical Properties of Vitamin A and Carotenoids
  • Physiological Functions of Vitamin A
  • Absorption, Transport, Storage, and Metabolism of Vitamin A and Carotenoids
  • Retinol-Binding Proteins
  • Nutritional Considerations of Vitamin A
  • 31.
  • Vitamin D
  • Steven K. Clinton
  • Efferent Signals
  • Dietary and Endogenous Sources of Vitamin D
  • Biological Actions of Vitamin D
  • Evaluation of Vitamin D Status
  • Dietary Sources of Vitamin D
  • Solar Contribution to Vitamin D Status
  • Vitamin D Toxicity
  • Dietary Reference Intakes for Vitamin D
  • Vitamin D and Health Outcomes
  • Controversy Over Recommendations for Vitamin D Intake and Status Testing
  • Unit VII
  • Importance of Diet and Exercise in Prevention of Overweight and Obesity
  • Minerals and Water
  • 32.
  • Calcium and Phosphorus
  • Sue A. Shapses
  • Chemical Properties of Calcium
  • Chemical Properties of Phosphate
  • Physiological and Metabolic Functions of Calcium and Phosphate
  • Hormonal Regulation of Calcium and Phosphate Metabolism
  • Calcium and Phosphate Homeostasis
  • Dietary Sources, Bioavailability, and Recommended Intakes for Calcium and Phosphorus
  • Contents note continued:
  • 23.
  • Calcium and Phosphate Deficiency, Excess, and Assessment of Status
  • Clinical Disorders Involving Altered Calcium and Phosphate Levels
  • 33.
  • Magnesium
  • Jurgen Vormann
  • Chemistry of Magnesium
  • Absorption, Bioavailability, and Excretion of Magnesium
  • Body Magnesium Content
  • Physiological Roles of Magnesium
  • Food Sources, Recommended Intakes, and Dietary Intakes of Magnesium
  • Disturbances of Energy Balance
  • Magnesium Depletion
  • Diagnosis of Magnesium Deficiency
  • Magnesium Toxicity
  • Magnesium and Disease Risks
  • Conclusion
  • 34.
  • Sodium, Chloride, and Potassium
  • Hwai-Ping Sheng
  • Functions and Distribution of Sodium, Chloride, and Potassium
  • Sodium, Chloride, and Potassium Balance
  • Christopher A. Taylor
  • Regulation of Sodium, Chloride, and Potassium Balance
  • Interactions Among Systems in Volume Regulation
  • Sodium and Chloride Imbalance and Its Consequences
  • Potassium Imbalance and Its Consequences
  • Nutritional Considerations
  • 35.
  • Body Fluids and Water Balance
  • Hwai-Ping Sheng
  • Physiological Functions of Water
  • Body Water Compartments
  • Adipose Tissue in Energy Balance
  • Water Balance
  • Renal Excretion of Water
  • Regulation of Water Balance
  • Water Imbalance and Its Consequences
  • 36.
  • Iron
  • Robert R. Crichton
  • Biological Functions of Iron
  • Proteins of Iron Transport, Storage, and Recycling
  • Body Iron Compartments and Daily Iron Exchange
  • Obesity
  • Internal Iron Exchange and Cellular Iron Metabolism
  • External Iron Exchange, Iron Absorption, and Systemic Iron Homeostasis
  • Dietary Reference Intakes for Iron
  • Iron Deficiency
  • Iron Excess
  • 37.
  • Zinc, Copper, and Manganese in Enzyme Systems
  • Arthur Grider
  • Absorption
  • Selected Functions of Zinc, Copper, and Manganese
  • Lipodystrophy
  • Assessment of Zinc, Copper, and Manganese Status and Deficiency Symptoms
  • Dietary Reference Intakes and Food Sources of Zinc, Copper, and Manganese
  • Toxicity of Zinc, Copper, and Manganese
  • 38.
  • Iodine
  • Hedley C. Freake
  • Production and Metabolism of Thyroid Hormones
  • Mechanism of Action of Thyroid Hormones
  • Physiological Functions of Thyroid Hormones
  • Iodine Deficiency
  • Starvation and Protein-Energy Malnutrition
  • Dietary Recommendations, Dietary Intake, and Toxicity
  • 39.
  • Selenium
  • Gerald F. Combs
  • Chemistry of Selenium
  • Utilization of Dietary Selenium
  • Selenoproteins
  • Tissue Distribution of Selenium
  • Nutritional Essentiality of Selenium
  • Selenium Toxicity
  • Definitions of PEM
  • Selenium Anticarcinogenesis
  • Human Selenium Requirements
  • Selenium Intakes
  • 40.
  • Fluoride
  • Gary M. Whitford
  • Dental Fluorosis and Dental Caries
  • Fluoride Intake
  • Fluoride Physiology
  • Acute Fluoride Toxicity
  • Unit VI
  • Chronic Fluoride Toxicity
  • 41.
  • Molybdenum and Beneficial Bioactive Trace Elements
  • Forrest H. Nielsen
  • Definition of Ultratrace Elements
  • Molybdenum
  • Boron
  • Chromium
  • Silicon
  • Vitamins
  • 21.
  • 24.
  • Niacin, Riboflavin, and Thiamin
  • W. Todd Penberthy
  • Niacin
  • Niacin History
  • Niacin Nomenclature, Structure, and Biochemistry
  • Niacin Physiological Function
  • Proteins That Require Niacin
  • Niacin Sources, Chemical Stability, and ADMET
  • Biochemical Assessment of Niacin Nutriture, Dietary Requirements, and High-Dose Responses
  • Cellular and Whole-Animal Energetics
  • Riboflavin
  • Riboflavin History
  • Riboflavin Nomenclature, Structure, and Biochemistry
  • Riboflavin Physiological Function
  • Proteins That Require Riboflavin
  • Riboflavin Sources, Chemical Stability, and ADMET
  • Biochemical Assessment of Riboflavin Nutriture and Dietary Requirements
  • Thiamin
  • Thiamin History
  • Thiamin Nomenclature, Structure, and Biochemistry
  • Matthew W. Hulver
  • Thiamin Physiological Function
  • Proteins That Require Thiamin
  • Thiamin Sources, Chemical Stability, and ADMET
  • Biochemical Assessment of Thiamin Nutriture and Dietary Requirements
  • Interdependence of B3, B2, and B1
  • 25.
  • Folate, Choline, Vitamin B12, and Vitamin B6
  • Barry Shane
  • Folate
  • Chemistry of Folate
  • Cellular Energetics
  • Sources of Folate
  • Folate Absorption
  • Folate Bioavailability
  • Transport of Folate
  • Tissue Accumulation of Folate
  • Folate Turnover
  • Metabolic Functions of Folate
  • Folate Deficiency: Symptoms, Metabolic Bases, and Disease
  • Folate Status Assessment
  • Folate Dietary Recommendations
  • Whole-Animal Energetics
  • Folate Toxicity
  • Choline
  • Choline Chemistry
  • Food Sources of Choline
  • Choline Absorption
  • Choline Bioavailablity
  • Transport of Choline
  • Metabolism of Choline
  • Physiological Functions of Choline
  • Choline Deficiency
  • 22.
  • Choline and Disease
  • Choline Homeostasis
  • Status Assessment of Choline
  • Dietary Recommendations, Factors Affecting Dietary Requirements, and Dietary Choline Intake
  • Choline Toxicity
  • Vitamin B12
  • Chemistry of Vitamin B12
  • Sources of Vitamin B12
  • Absorption and Bioavailability of Vitamin B12
  • Plasma Transport, Tissue Uptake, and Turnover of Vitamin B12
  • Control of Energy Balance
  • Intracellular Metabolism and Metabolic Functions of Vitamin B12
  • Vitamin B12 Deficiency: Symptoms and Metabolic Bases
  • Vitamin B12 Requirements
  • Vitamin B12 Dietary Intakes
  • Vitamin B12 Toxicity
  • Vitamin B6
  • Chemistry of Vitamin B6
  • Sources of Vitamin B6
  • Absorption of Vitamin B6
  • Bioavailability of Vitamin B6
Dimensions
27 cm.
Edition
3rd ed.
Extent
xix, 948 p.
Isbn
9781437709599
Isbn Type
(pbk.)
Lccn
2011031519
Other physical details
ill.
System control number
  • (CaMWU)u2512081-01umb_inst
  • 2567971
  • (Sirsi) i9781437709599
  • (DNLM)101565397
  • (OCoLC)743275919

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