The Resource Cellular respiration and carcinogenesis, Shireesh P. Apte, Rangaprasad Sarangarajan, editors ; foreword by Gregg L. Semenza, (electronic resource)

Cellular respiration and carcinogenesis, Shireesh P. Apte, Rangaprasad Sarangarajan, editors ; foreword by Gregg L. Semenza, (electronic resource)

Label
Cellular respiration and carcinogenesis
Title
Cellular respiration and carcinogenesis
Statement of responsibility
Shireesh P. Apte, Rangaprasad Sarangarajan, editors ; foreword by Gregg L. Semenza
Contributor
Subject
Genre
Language
  • eng
  • eng
Summary
Cellular Respiration and Carcinogenesis informs the reader about both basic and recent research in the field of cellular respiration and the effects of its dysfunction, alteration or attenuation on the development of cancer. This masterfully compiled text by leading experts in the field, offers the reader a fundamental understanding about how oxygen sensing and/or availability, programmed cell death, immune recognition and response and glucose metabolism are intimately linked with the two major mechanisms or pathways of cellular respiration; oxidative phosphorylation and glycolysis. The editors and contributing authors proficiently and unequivocally address the effects of dysfunction of the mitochondrial oxidative phosphorylation/glycolysis (cellular respiration) mechanisms and pathways on the development of cancer. While it remains true that there are no universal truths in cancer, Cellular Respiration and Carcinogenesis opens the dialogue that the etiology of cancer can usually be associated with and significantly attributed to the failure of one or multiple pathways of oxidative phosphorylation to normally burn fuel to generate energy, vis-à-vis the Warburg hypothesis. Keeping with its cutting-edge nature, Cellular Respiration and Carcinogenesis provides the first glimpse of cautionary evidence based counterbalance to the recent and rapidly proliferating notion that utilization of fuel primarily via glycolysis is a hallmark of cancer development. About the Editors: Shireesh P.Apte, Ph.D has 10+ years experience in the pharmaceutical industry researching and formulating anti-cancer drugs. He holds one US patent and has 10+ related publications. He is a member of the US Pharmacopoeia excipients expert committee. Rangaprasad Sarangarajan, Ph.D. has over 10 years of research experience in an academic setting with extensive publications in areas of pharmacology & toxicology with focus on cancer treatment. He is active member of various professional organizations including the Society of Toxicology, American Society for Pharmacology & Toxicology and Pan American Society for Pigment Cell Research
Cataloging source
MiAaPQ
Dewey number
616.99/4
Illustrations
illustrations
Index
index present
Language note
English
LC call number
RC268.48
LC item number
.C45 2009
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
http://library.link/vocab/relatedWorkOrContributorName
  • Apte, Shireesh P
  • Sarangarajan, Rangaprasad
  • Semenza, Gregg L
http://library.link/vocab/subjectName
  • Tumors
  • Cell respiration
Label
Cellular respiration and carcinogenesis, Shireesh P. Apte, Rangaprasad Sarangarajan, editors ; foreword by Gregg L. Semenza, (electronic resource)
Instantiates
Publication
Note
Description based upon print version of record
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
cr
Content category
text
Content type code
txt
Contents
Oxidative Phosphorylation and Cancer: The Ongoing Warburg Hypothesis -- The Electron Transport Chain and Carcinogenesis -- Respiratory Control of Redox Signaling and Cancer -- Cellular Respiration and Dedifferentiation -- Cellular Adaptations to Oxidative Phosphorylation Defects in Cancer -- Regulation of Glucose and Energy Metabolism in Cancer Cells by Hypoxia Inducible Factor 1 -- The Role of Glycolysis in Cellular Immortalization -- Metabolic Modulation of Carcinogenesis -- Mitochondrial DNA Mutations in Tumors -- Cellular Respiration and Tumor Suppressor Genes -- Uncoupling Cellular Respiration: A Link to Cancer Cell Metabolism and Immune Privilege -- How Cancer Cells Escape Death
Dimensions
unknown
Extent
1 online resource (205 p.)
Form of item
online
Isbn
9781597454353
Media category
computer
Media type code
c
Other control number
10.1007/978-1-59745-435-3
Specific material designation
remote
System control number
  • (CKB)1000000000546448
  • (EBL)417461
  • (OCoLC)477154579
  • (SSID)ssj0000331081
  • (PQKBManifestationID)11279689
  • (PQKBTitleCode)TC0000331081
  • (PQKBWorkID)10326029
  • (PQKB)11137995
  • (DE-He213)978-1-59745-435-3
  • (MiAaPQ)EBC417461
  • (EXLCZ)991000000000546448
Label
Cellular respiration and carcinogenesis, Shireesh P. Apte, Rangaprasad Sarangarajan, editors ; foreword by Gregg L. Semenza, (electronic resource)
Publication
Note
Description based upon print version of record
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
cr
Content category
text
Content type code
txt
Contents
Oxidative Phosphorylation and Cancer: The Ongoing Warburg Hypothesis -- The Electron Transport Chain and Carcinogenesis -- Respiratory Control of Redox Signaling and Cancer -- Cellular Respiration and Dedifferentiation -- Cellular Adaptations to Oxidative Phosphorylation Defects in Cancer -- Regulation of Glucose and Energy Metabolism in Cancer Cells by Hypoxia Inducible Factor 1 -- The Role of Glycolysis in Cellular Immortalization -- Metabolic Modulation of Carcinogenesis -- Mitochondrial DNA Mutations in Tumors -- Cellular Respiration and Tumor Suppressor Genes -- Uncoupling Cellular Respiration: A Link to Cancer Cell Metabolism and Immune Privilege -- How Cancer Cells Escape Death
Dimensions
unknown
Extent
1 online resource (205 p.)
Form of item
online
Isbn
9781597454353
Media category
computer
Media type code
c
Other control number
10.1007/978-1-59745-435-3
Specific material designation
remote
System control number
  • (CKB)1000000000546448
  • (EBL)417461
  • (OCoLC)477154579
  • (SSID)ssj0000331081
  • (PQKBManifestationID)11279689
  • (PQKBTitleCode)TC0000331081
  • (PQKBWorkID)10326029
  • (PQKB)11137995
  • (DE-He213)978-1-59745-435-3
  • (MiAaPQ)EBC417461
  • (EXLCZ)991000000000546448

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