The Resource Chromatin Architecture : Advances From High-resolution Single Molecule DNA Imaging, by Kirti Prakash, (electronic resource)

Chromatin Architecture : Advances From High-resolution Single Molecule DNA Imaging, by Kirti Prakash, (electronic resource)

Label
Chromatin Architecture : Advances From High-resolution Single Molecule DNA Imaging
Title
Chromatin Architecture
Title remainder
Advances From High-resolution Single Molecule DNA Imaging
Statement of responsibility
by Kirti Prakash
Creator
Author
Author
Subject
Language
eng
Summary
This book sheds new light on the current state of knowledge concerning chromatin organization. Particular emphasis is given to the new imaging potential offered by super-resolution microscopy, which allows DNA imaging with a very high labeling density. From the early work on chromosomes by Walther Flemming in the nineteenth century to recent advances in genomics, the history of chromatin research now spans more than a century. The various milestones, such as the discovery of the double helix structure, the sequencing of the human genome, and the recent description of the genome in 3D space, show that understanding chromatin and chromosome function requires a clear understanding of its structure. Presenting cutting-edge data from super-resolution single molecule microscopy, the book demonstrates that chromatin manifests several levels of folding, from nucleosomes to chromosomes. Chromatin domains emerge as a new fundamental building block of chromatin architecture, with functions possibly related to gene regulation. A detailed description of chromatin folding in the pachytene stage of meiosis serves as a model for exploring this functionality, showing the apparent interplay between structure, function, and epigenetic regulation. Lastly, the book discusses possible new avenues of innovation to describe chromatin’s organization and functions. Gathering essential insights on chromatin architecture, the book offers students an introduction to microscopy and its application to chromatin organization, while also providing advanced readers with new ideas for future research
Member of
http://library.link/vocab/creatorName
Prakash, Kirti
Dewey number
571.6
http://bibfra.me/vocab/relation/httpidlocgovvocabularyrelatorsaut
-6sOU3twVIU
Image bit depth
0
LC call number
QH573-671
Literary form
non fiction
Nature of contents
dictionaries
Series statement
Springer Theses, Recognizing Outstanding Ph.D. Research,
http://library.link/vocab/subjectName
  • Cytology
  • Nucleic acids
  • Spectroscopy
  • Cell Biology
  • Spectroscopy and Microscopy
  • Nucleic Acid Chemistry
  • Spectroscopy/Spectrometry
Label
Chromatin Architecture : Advances From High-resolution Single Molecule DNA Imaging, by Kirti Prakash, (electronic resource)
Instantiates
Publication
Note
"Doctoral Thesis accepted by Institute of Molecular Biology, Mainz and Heidelberg University, Germany."
Antecedent source
mixed
Bibliography note
Includes bibliographical references at the end of each chapters
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
A Condensed History of Chromatin Research -- Investigating Chromatin Organisation Using Single Molecule Localisation Microscopy -- Structure, Function and Dynamics of Chromatin -- Periodic and Symmetric Organisation of Meiotic Chromosomes -- Conclusions -- Appendices
Dimensions
unknown
Edition
1st ed. 2017.
Extent
1 online resource (LIII, 152 p. 101 illus., 50 illus. in color.)
File format
multiple file formats
Form of item
online
Isbn
9783319521831
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-3-319-52183-1
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote
System control number
  • (CKB)3710000001072449
  • (DE-He213)978-3-319-52183-1
  • (MiAaPQ)EBC4811123
  • (EXLCZ)993710000001072449
Label
Chromatin Architecture : Advances From High-resolution Single Molecule DNA Imaging, by Kirti Prakash, (electronic resource)
Publication
Note
"Doctoral Thesis accepted by Institute of Molecular Biology, Mainz and Heidelberg University, Germany."
Antecedent source
mixed
Bibliography note
Includes bibliographical references at the end of each chapters
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
A Condensed History of Chromatin Research -- Investigating Chromatin Organisation Using Single Molecule Localisation Microscopy -- Structure, Function and Dynamics of Chromatin -- Periodic and Symmetric Organisation of Meiotic Chromosomes -- Conclusions -- Appendices
Dimensions
unknown
Edition
1st ed. 2017.
Extent
1 online resource (LIII, 152 p. 101 illus., 50 illus. in color.)
File format
multiple file formats
Form of item
online
Isbn
9783319521831
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-3-319-52183-1
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote
System control number
  • (CKB)3710000001072449
  • (DE-He213)978-3-319-52183-1
  • (MiAaPQ)EBC4811123
  • (EXLCZ)993710000001072449

Library Locations

  • Albert D. Cohen Management LibraryBorrow it
    181 Freedman Crescent, Winnipeg, MB, R3T 5V4, CA
    49.807878 -97.129961
  • Architecture/Fine Arts LibraryBorrow it
    84 Curry Place, Winnipeg, MB, CA
    49.807716 -97.136226
  • Archives and Special CollectionsBorrow it
    25 Chancellors Circle (Elizabeth Dafoe Library), Room 330, Winnipeg, MB, R3T 2N2, CA
    49.809961 -97.131878
  • Bibliothèque Alfred-Monnin (Université de Saint-Boniface)Borrow it
    200, avenue de la Cathédrale, Local 2110, Winnipeg, MB, R2H 0H7, CA
    49.888861 -97.119735
  • Bill Larson Library (Grace Hospital)Borrow it
    300 Booth Drive, G-227, Winnipeg, MB, R3J 3M7, CA
    49.882400 -97.276436
  • Carolyn Sifton - Helene Fuld Library (St. Boniface General Hospital)Borrow it
    409 Tache Avenue, Winnipeg, MB, R2H 2A6, CA
    49.883388 -97.126050
  • Concordia Hospital LibraryBorrow it
    1095 Concordia Avenue, Winnipeg, MB, R2K 3S8, CA
    49.913252 -97.064683
  • Donald W. Craik Engineering LibraryBorrow it
    75B Chancellors Circle (Engineering Building E3), Room 361, Winnipeg, MB, R3T 2N2, CA
    49.809053 -97.133292
  • E.K. Williams Law LibraryBorrow it
    224 Dysart Road, Winnipeg, MB, R3T 5V4, CA
    49.811829 -97.131017
  • Eckhardt-Gramatté Music LibraryBorrow it
    136 Dafoe Road (Taché Arts Complex), Room 257, Winnipeg, MB, R3T 2N2, CA
    49.807964 -97.132222
  • Elizabeth Dafoe LibraryBorrow it
    25 Chancellors Circle, Winnipeg, MB, R3T 2N2, CA
    49.809961 -97.131878
  • Fr. H. Drake Library (St. Paul's College)Borrow it
    70 Dysart Road, Winnipeg, MB, R3T 2M6, CA
    49.810605 -97.138184
  • J.W. Crane Memorial Library (Deer Lodge Centre)Borrow it
    2109 Portage Avenue, Winnipeg, MB, R3J 0L3, CA
    49.878000 -97.235520
  • Libraries Annex (not open to the public; please see web page for details)Borrow it
    25 Chancellors Circle (in the Elizabeth Dafoe Library), Winnipeg, MB, R3T 2N2, CA
    49.809961 -97.131878
  • Neil John Maclean Health Sciences LibraryBorrow it
    727 McDermot Avenue (Brodie Centre), 200 Level, Winnipeg, MB, R3E 3P5, CA
    49.903563 -97.160554
  • Sciences and Technology LibraryBorrow it
    186 Dysart Road, Winnipeg, MB, R3T 2M8, CA
    49.811526 -97.133257
  • Seven Oaks General Hospital LibraryBorrow it
    2300 McPhillips Street, Winnipeg, MB, R2V 3M3, CA
    49.955177 -97.148865
  • Sister St. Odilon Library (Misericordia Health Centre)Borrow it
    99 Cornish Avenue, Winnipeg, MB, R3C 1A2, CA
    49.879592 -97.160425
  • St. John's College LibraryBorrow it
    92 Dysart Road, Winnipeg, MB, R3T 2M5, CA
    49.811242 -97.137156
  • Victoria General Hospital LibraryBorrow it
    2340 Pembina Highway, Winnipeg, MB, R3T 2E8, CA
    49.806755 -97.152739
  • William R Newman Library (Agriculture)Borrow it
    66 Dafoe Road, Winnipeg, MB, R3T 2R3, CA
    49.806936 -97.135525
Processing Feedback ...