The Resource Claudins, edited by Alan S.L. Yu, (electronic resource)

Claudins, edited by Alan S.L. Yu, (electronic resource)

Label
Claudins
Title
Claudins
Statement of responsibility
edited by Alan S.L. Yu
Contributor
Subject
Genre
Language
  • eng
  • eng
Summary
This volume of Current Topics in Membranes focuses on Membrane Protein Crystallization, beginning with a review of past successes and general trends, then further discussing challenges of mebranes protein crystallization, cell free production of membrane proteins and novel lipids for membrane protein crystallization. This publication also includes tools to enchance membrane protein crystallization, technique advancements, and crystallization strategies used for photosystem I and its complexes, establishing Membrane Protein Crystallization as a needed, practical reference for researche
Member of
Is Subseries of
Cataloging source
MiAaPQ
Dewey number
571.6
Illustrations
  • illustrations
  • plates
Index
index present
Language note
English
LC call number
QH603.C4
LC item number
C53 2010
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
http://library.link/vocab/relatedWorkOrContributorName
Yu, Alan S. L
Series statement
Current topics in membranes
Series volume
v. 65
http://library.link/vocab/subjectName
  • Tight junctions (Cell biology)
  • Membrane proteins
Label
Claudins, edited by Alan S.L. Yu, (electronic resource)
Instantiates
Publication
Note
Description based upon print version of record
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
cr
Content category
text
Content type code
txt
Contents
  • Front Cover; Current Topics in Membranes; Copyright Page; Dedication; Contents; Contributors; Preface; Previous Volumes in Series; Chapter 1: Introduction: Claudins, Tight Junctions, and the Paracellular Barrier; I. Overview; II. Introduction; III. History of the Identification of Claudins; A. Identification of TJ-Associated Proteins by Immunological Approaches; B. Identification of the Claudin Family; IV. Structure of Claudins; V. TJ Formation by the Claudin Family; VI. Complex Structure of TJ Strands Formed by Multiple Claudin Subtypes
  • VII. Functional Diversity of the Barrier Property of Claudin-Based TJsVIII. In vivo Functions of Claudins: Claudin-Deficient Mice and Hereditary Diseases with Claudin Mutations; IX. Dynamic Behavior of Claudin-Based TJs; X. Summary and Future Perspectives; Acknowledgments; References; Chapter 2: Morphological Studies of Claudins in the Tight Junction; I. Overview; II. Background; III. Claudins but not Occludin Form Tight Junction Strands; IV. Morphological Tools for the Study of Tight Junctions; A. Localization of Tight Junction Proteins by Immunofluorescence Microscopy
  • B. Localization of Tight Junction Proteins at the Ultrastructural LevelV. Claudins are Relatively Stable Components of the Tight Junction; VI. Claudin-Claudin Interactions; VII. Claudins, Regulators of Paracellular Ion Selectivity; VIII. Summary; References; Chapter 3: Biophysical Methods to Study Tight Junction Permeability; I. Overview; II. Introduction; III. Resistance Measurements; A. Transepithelial Resistance (TER, Rt); B. Chopstick Electrodes; C. Ussing Chamber; D. Impedance Spectroscopy; E. One-Path Impedance Spectroscopy; F. Two-Path Impedance Spectroscopy; G. Conductance Scanning
  • IV. Ion Permeability MeasurementsA. Ion Flux Measurements; B. Dilution and Biionic Potentials; C. Conductance Measurements; V. Fluxes of Uncharged Paracellular Tracers; VI. Paracellular Water Transport; VII. Experimental Strategies for TJ Perturbation; A. Cell Culture Models: Overexpression and Knockdown; B. In Vivo Models: Knockout Mice; C. Established Mouse Models; VIII. Conclusion; References; Chapter 4: Structure-Function Studies of the Claudin Pore; I. Overview; II. Introduction; III. Methodological Challenges in Measuring Pore Function of Individual Claudins
  • IV. The First Extracellular Domain of Claudins Lines the Paracellular PoreV. Molecular Basis of Charge Selectivity; VI. Size of Claudin Pores; VII. Mapping Residues onto the Structure of the Claudin Pore by Cysteine Mutagenesis; VIII. Stoichiometry of Claudin Pores; IX. Conclusions; References; Chapter 5: The Investigation of cis- and trans-Interactions Between Claudins; I. Overview; II. Introduction; III. Estimation of Interactions, Without Differentiation Between cis- and trans-Interaction; A. Conventional Techniques; B. Proteomic Approaches for Identifying Interaction Partners of Claudins
  • IV. Analysis of cis-Interactions Along the Plasma Membrane
Dimensions
unknown
Edition
1st ed.
Extent
1 online resource (373 p.)
Form of item
online
Isbn
9781282700000
Media category
computer
Media type code
c
Specific material designation
remote
System control number
  • (CKB)2670000000034090
  • (EBL)632004
  • (OCoLC)689007501
  • (SSID)ssj0000434519
  • (PQKBManifestationID)11276849
  • (PQKBTitleCode)TC0000434519
  • (PQKBWorkID)10403369
  • (PQKB)11342246
  • (MiAaPQ)EBC632004
  • (EXLCZ)992670000000034090
Label
Claudins, edited by Alan S.L. Yu, (electronic resource)
Publication
Note
Description based upon print version of record
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
cr
Content category
text
Content type code
txt
Contents
  • Front Cover; Current Topics in Membranes; Copyright Page; Dedication; Contents; Contributors; Preface; Previous Volumes in Series; Chapter 1: Introduction: Claudins, Tight Junctions, and the Paracellular Barrier; I. Overview; II. Introduction; III. History of the Identification of Claudins; A. Identification of TJ-Associated Proteins by Immunological Approaches; B. Identification of the Claudin Family; IV. Structure of Claudins; V. TJ Formation by the Claudin Family; VI. Complex Structure of TJ Strands Formed by Multiple Claudin Subtypes
  • VII. Functional Diversity of the Barrier Property of Claudin-Based TJsVIII. In vivo Functions of Claudins: Claudin-Deficient Mice and Hereditary Diseases with Claudin Mutations; IX. Dynamic Behavior of Claudin-Based TJs; X. Summary and Future Perspectives; Acknowledgments; References; Chapter 2: Morphological Studies of Claudins in the Tight Junction; I. Overview; II. Background; III. Claudins but not Occludin Form Tight Junction Strands; IV. Morphological Tools for the Study of Tight Junctions; A. Localization of Tight Junction Proteins by Immunofluorescence Microscopy
  • B. Localization of Tight Junction Proteins at the Ultrastructural LevelV. Claudins are Relatively Stable Components of the Tight Junction; VI. Claudin-Claudin Interactions; VII. Claudins, Regulators of Paracellular Ion Selectivity; VIII. Summary; References; Chapter 3: Biophysical Methods to Study Tight Junction Permeability; I. Overview; II. Introduction; III. Resistance Measurements; A. Transepithelial Resistance (TER, Rt); B. Chopstick Electrodes; C. Ussing Chamber; D. Impedance Spectroscopy; E. One-Path Impedance Spectroscopy; F. Two-Path Impedance Spectroscopy; G. Conductance Scanning
  • IV. Ion Permeability MeasurementsA. Ion Flux Measurements; B. Dilution and Biionic Potentials; C. Conductance Measurements; V. Fluxes of Uncharged Paracellular Tracers; VI. Paracellular Water Transport; VII. Experimental Strategies for TJ Perturbation; A. Cell Culture Models: Overexpression and Knockdown; B. In Vivo Models: Knockout Mice; C. Established Mouse Models; VIII. Conclusion; References; Chapter 4: Structure-Function Studies of the Claudin Pore; I. Overview; II. Introduction; III. Methodological Challenges in Measuring Pore Function of Individual Claudins
  • IV. The First Extracellular Domain of Claudins Lines the Paracellular PoreV. Molecular Basis of Charge Selectivity; VI. Size of Claudin Pores; VII. Mapping Residues onto the Structure of the Claudin Pore by Cysteine Mutagenesis; VIII. Stoichiometry of Claudin Pores; IX. Conclusions; References; Chapter 5: The Investigation of cis- and trans-Interactions Between Claudins; I. Overview; II. Introduction; III. Estimation of Interactions, Without Differentiation Between cis- and trans-Interaction; A. Conventional Techniques; B. Proteomic Approaches for Identifying Interaction Partners of Claudins
  • IV. Analysis of cis-Interactions Along the Plasma Membrane
Dimensions
unknown
Edition
1st ed.
Extent
1 online resource (373 p.)
Form of item
online
Isbn
9781282700000
Media category
computer
Media type code
c
Specific material designation
remote
System control number
  • (CKB)2670000000034090
  • (EBL)632004
  • (OCoLC)689007501
  • (SSID)ssj0000434519
  • (PQKBManifestationID)11276849
  • (PQKBTitleCode)TC0000434519
  • (PQKBWorkID)10403369
  • (PQKB)11342246
  • (MiAaPQ)EBC632004
  • (EXLCZ)992670000000034090

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