The Resource Comparative Biology of Aging, edited by Norman S. Wolf, (electronic resource)

Comparative Biology of Aging, edited by Norman S. Wolf, (electronic resource)

Label
Comparative Biology of Aging
Title
Comparative Biology of Aging
Statement of responsibility
edited by Norman S. Wolf
Contributor
Editor
Editor
Subject
Language
  • eng
  • eng
Summary
Cover copy: Wolf, Norman (ed.), The Comparative Biology of Aging The processes of aging and death remain one of the most fascinating, and mysterious, areas of biological research. Huge anomalies between species raise questions the answers to which could have fundamental implications for the field of medical science. As scientists unlock the secrets of the exceptionally long-lived little brown bat (up to 34 years), or the common Budgerigar which despite having a metabolic rate 1.5 times that of a laboratory mouse, can live for up to 20 years, it has become more important than ever to be able to make a comparative analysis of the various species used in research. Dealing with every one of the species that are employed in laboratory research, this is the first book on the subject of aging that provides detailed comparative data for age-related changes in its subjects. It does so at the level of the whole animal, its organs, organelles and molecules. The comparative data, supplied in 15 chapters by leading experts, provides information on fields as disparate as telomere function and loss, the importance of the Sirtuins and Tor, the influence of hormones on lifespans, the relationship between body size and lifespan, the effects of restricted calorific intake, age-related changes in cell replication, and DNA damage and repair. Chapters are devoted to cardiac aging, comparative skeletal muscle aging, the aging of the nervous and immune systems, the comparative biology of lyosomal function and how it is affected by age, and many other key areas of research. This much-needed text will provide scientists working in a wide spectrum of fields with key data to aid them in their studies
Dewey number
571.87819
http://bibfra.me/vocab/relation/httpidlocgovvocabularyrelatorsedt
GuN5_eVa2hs
Language note
English
LC call number
R-RZ
Literary form
non fiction
Nature of contents
dictionaries
http://library.link/vocab/relatedWorkOrContributorName
Wolf, Norman S.
http://library.link/vocab/subjectName
  • Medicine
  • Geriatrics
  • Cytology
  • Cell physiology
  • Biomedicine general
  • Geriatrics/Gerontology
  • Oxidative Stress
  • Cell Physiology
Label
Comparative Biology of Aging, edited by Norman S. Wolf, (electronic resource)
Instantiates
Publication
Note
Includes index
Carrier category
online resource
Carrier category code
cr
Content category
text
Content type code
txt
Contents
Introduction: Lifespans and Pathologies Present at Death in Laboratory Animals -- Animal Size, Metabolic Rate, and Survival, Among and Within Species -- Hormonal Influences on Aging and Lifespan -- Exploring Mechanisms of Aging Retardation by Caloric Restriction: Studies in Model Organisms and Mammals -- Cell Replication Rates In Vivo and In Vitro and Wound Healing as Affected by Animal Age, Diet, and Species -- Sirtuin Function in Longevity -- The Role of TOR Signaling in Aging -- Mitochondria, Oxidative Damage and Longevity: What Can Comparative Biology Teach Us? -- Comparative Genomics of Aging -- Changes in Lysosomes and Their Autophagic Function in Aging: The Comparative Biology of Lysosomal Function -- Telomeres and Telomerase -- Cardiac Aging -- Comparative Skeletal Muscle Aging -- Aging of the Nervous System -- Aging of the Immune System Across Different Species
Dimensions
unknown
Edition
1st ed. 2010.
Extent
1 online resource (396 p.)
Form of item
online
Isbn
9786612925139
Media category
computer
Media type code
c
Other control number
10.1007/978-90-481-3465-6
Specific material designation
remote
System control number
  • (CKB)2670000000007206
  • (EBL)511480
  • (OCoLC)710992210
  • (SSID)ssj0000372258
  • (PQKBManifestationID)11256799
  • (PQKBTitleCode)TC0000372258
  • (PQKBWorkID)10421839
  • (PQKB)10581220
  • (DE-He213)978-90-481-3465-6
  • (MiAaPQ)EBC511480
  • (EXLCZ)992670000000007206
Label
Comparative Biology of Aging, edited by Norman S. Wolf, (electronic resource)
Publication
Note
Includes index
Carrier category
online resource
Carrier category code
cr
Content category
text
Content type code
txt
Contents
Introduction: Lifespans and Pathologies Present at Death in Laboratory Animals -- Animal Size, Metabolic Rate, and Survival, Among and Within Species -- Hormonal Influences on Aging and Lifespan -- Exploring Mechanisms of Aging Retardation by Caloric Restriction: Studies in Model Organisms and Mammals -- Cell Replication Rates In Vivo and In Vitro and Wound Healing as Affected by Animal Age, Diet, and Species -- Sirtuin Function in Longevity -- The Role of TOR Signaling in Aging -- Mitochondria, Oxidative Damage and Longevity: What Can Comparative Biology Teach Us? -- Comparative Genomics of Aging -- Changes in Lysosomes and Their Autophagic Function in Aging: The Comparative Biology of Lysosomal Function -- Telomeres and Telomerase -- Cardiac Aging -- Comparative Skeletal Muscle Aging -- Aging of the Nervous System -- Aging of the Immune System Across Different Species
Dimensions
unknown
Edition
1st ed. 2010.
Extent
1 online resource (396 p.)
Form of item
online
Isbn
9786612925139
Media category
computer
Media type code
c
Other control number
10.1007/978-90-481-3465-6
Specific material designation
remote
System control number
  • (CKB)2670000000007206
  • (EBL)511480
  • (OCoLC)710992210
  • (SSID)ssj0000372258
  • (PQKBManifestationID)11256799
  • (PQKBTitleCode)TC0000372258
  • (PQKBWorkID)10421839
  • (PQKB)10581220
  • (DE-He213)978-90-481-3465-6
  • (MiAaPQ)EBC511480
  • (EXLCZ)992670000000007206

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