The Resource Crystals, x-rays, and proteins : comprehensive protein crystallography, Dennis Sherwood, Jon Cooper

Crystals, x-rays, and proteins : comprehensive protein crystallography, Dennis Sherwood, Jon Cooper

Label
Crystals, x-rays, and proteins : comprehensive protein crystallography
Title
Crystals, x-rays, and proteins
Title remainder
comprehensive protein crystallography
Statement of responsibility
Dennis Sherwood, Jon Cooper
Creator
Contributor
Subject
Language
eng
Summary
"A complete account of the theory of the diffraction of x-rays by crystals with particular reference to the processes of determining the structures of protein molecules, this book is aimed primarily at structural biologists and biochemists but will also be valuable to those entering the field with a background in physical sciences or chemistry. It may be used at any post-school level, and develops from first principles all relevant mathematics, diffraction and wave theory, assuming no mathematical knowledge beyond integral calculus. The book covers a host of important topics in the area, including:- The practical aspects of sample preparation and x-ray data collection, using both laboratory and synchrotron sources - Data analysis at both theoretical and practical levels- The important role played by the Patterson function in structure analysis by both molecular replacement and experimental phasing approaches - Methods for improving the resulting electron density map - The theoretical basis of methods used in refinement of protein crystal structures - In-depth explanation of the crucial task of defining the binding sites of ligands and drug molecules - The complementary roles of other diffraction methods which reveal further detail of great functional importance in a crystal structure"--Provided by publisher
Cataloging source
DNLM/DLC
http://library.link/vocab/creatorName
Sherwood, Dennis
Dewey number
612.8
Illustrations
illustrations
Index
index present
LC call number
QP551
LC item number
.S535 2011
Literary form
non fiction
Nature of contents
bibliography
NLM call number
QU 55
http://library.link/vocab/relatedWorkOrContributorName
  • Cooper, Jon
  • Sherwood, Dennis
http://library.link/vocab/subjectName
  • Proteins
  • X-ray crystallography
  • Proteins
  • Crystallography, X-Ray
  • Protein Conformation
Label
Crystals, x-rays, and proteins : comprehensive protein crystallography, Dennis Sherwood, Jon Cooper
Instantiates
Publication
Note
Update to: Crystals, X-rays, and proteins / Dennis Sherwood. 1976
Bibliography note
Includes bibliographical references and index
Contents
Machine generated contents note: -- 1. The crystalline state and its study2. Vector analysis and complex algebra3. Crystal systematics4. Waves and electromagnetic radiation5. Fourier transforms and convolutions6. Diffraction7. Diffraction from one-dimensional obstacles8. Diffraction from a three-dimensional lattice9. The contents of the unit cell10. Experimental methods: sample preparatio11. Experimental techniques: data collection and analysis12. The Phase problem and the Patterson function13. Molecular replacement14. Solving the phase problem experimentally15. Refinement16. Complementary crystallographic methods
Dimensions
26 cm.
Extent
xvii, 621 p.
Isbn
9780199559046
Isbn Type
(hbk. : alk. paper)
Lccn
2010032106
Other physical details
ill.
System control number
  • (CaMWU)u2157239-01umb_inst
  • 2283591
  • (Sirsi) i9780199559046
  • (OCoLC)655617172
Label
Crystals, x-rays, and proteins : comprehensive protein crystallography, Dennis Sherwood, Jon Cooper
Publication
Note
Update to: Crystals, X-rays, and proteins / Dennis Sherwood. 1976
Bibliography note
Includes bibliographical references and index
Contents
Machine generated contents note: -- 1. The crystalline state and its study2. Vector analysis and complex algebra3. Crystal systematics4. Waves and electromagnetic radiation5. Fourier transforms and convolutions6. Diffraction7. Diffraction from one-dimensional obstacles8. Diffraction from a three-dimensional lattice9. The contents of the unit cell10. Experimental methods: sample preparatio11. Experimental techniques: data collection and analysis12. The Phase problem and the Patterson function13. Molecular replacement14. Solving the phase problem experimentally15. Refinement16. Complementary crystallographic methods
Dimensions
26 cm.
Extent
xvii, 621 p.
Isbn
9780199559046
Isbn Type
(hbk. : alk. paper)
Lccn
2010032106
Other physical details
ill.
System control number
  • (CaMWU)u2157239-01umb_inst
  • 2283591
  • (Sirsi) i9780199559046
  • (OCoLC)655617172

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