The Resource Metal ions and neurodegenerative disorders, editor, Paolo Zatta, (electronic resource)

Metal ions and neurodegenerative disorders, editor, Paolo Zatta, (electronic resource)

Label
Metal ions and neurodegenerative disorders
Title
Metal ions and neurodegenerative disorders
Statement of responsibility
editor, Paolo Zatta
Contributor
Subject
Genre
Language
  • eng
  • eng
Summary
Numerous studies have established a clear connection between neuronal oxidative stress and several neurodegenerative diseases, with consequential damages to lipids, proteins, nucleic acids, etc. In addition, several modifications indicative of oxidative stress have been described in association with neurons, neurofibrillary tangles and senile plaques in Alzheimer's disease, including advanced glycation end products and free carbonyl oxidation. Oxidative damage and antioxidant responses are now well characterized, but sources of damaging free radicals are yet to be fully understood. Evidences
Cataloging source
MiAaPQ
Dewey number
616.80471
Illustrations
illustrations
Index
no index present
Language note
English
LC call number
RA1231.M52
LC item number
M47 2003
Literary form
non fiction
Nature of contents
dictionaries
http://library.link/vocab/relatedWorkOrContributorName
Zatta, Paolo
http://library.link/vocab/subjectName
  • Metal ions
  • Molecular neurobiology
  • Nervous system
  • Neurotoxicology
Label
Metal ions and neurodegenerative disorders, editor, Paolo Zatta, (electronic resource)
Instantiates
Publication
Note
Description based upon print version of record
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
cr
Content category
text
Content type code
txt
Contents
  • Contents ; Preface ; List of Contributors ; Chapter 1. Metal-Catalyzed Redox Activity in Neurodegenerative Disease ; 1. INTRODUCTION ; 1.1. Redox-Active Transition Metals in AD ; 1.2. Aggregation of Amyloid-B and Amyloid B Protein Precursor/Amyloid-p-Linked ROS Production
  • 1.3. Iron in Neurodegenerative Disease 1.4. Iron-Mediated Oxidative Stress in Parkinson's Disease ; 1.5. Manganese and Parkinson's Disease ; 1.6. Antioxidant and Transition Metal Homeostasis ; 1.7. CuZnSOD Mutations and Familial Amyotrophic Lateral Sclerosis ; 2. CONCLUSIONS
  • Chapter 2. Metals Distribution and Regionalization in the Brain 1. TRACE ELEMENT DISTRIBUTION IN NORMAL HUMAN BRAIN ; 1.1. Aluminum Iron Copper and Zinc Distribution in Normal Human Brain Sites in Relation to Age ; 1.2. Aluminum ; 1.3. Iron ; 1.4. Copper ; 1.5. Zinc
  • 2. TRACE ELEMENT IMBALANCES IN NEURODEGENERATIVE DISEASES 2.1. Aluminum Iron Copper and Zinc in Alzheimer's Disease ; 2.2. Factors Affecting the Final Results ; 2.3. Aluminum Iron Copper and Zinc in Parkinson's Disease
  • 2.4. Aluminum Iron Copper and Zinc in Western Pacific Parkinsonism-Dementia 2.5. Aluminum Iron Copper and Zinc in Amyotrophic Lateral Sclerosis ; 3. FINAL REMARKS ; Chapter 3. The Olfactory Pathway as a Route of Entry of Metals into the Brain ; 1. INTRODUCTION
  • 2. ANATOMY OF THE OLFACTORY SYSTEM
Dimensions
unknown
Extent
1 online resource (538 p.)
Form of item
online
Isbn
9781281956088
Media category
computer
Media type code
c
Specific material designation
remote
System control number
  • (CKB)1000000000537895
  • (EBL)1681633
  • (OCoLC)815755899
  • (SSID)ssj0000201641
  • (PQKBManifestationID)11184391
  • (PQKBTitleCode)TC0000201641
  • (PQKBWorkID)10245481
  • (PQKB)10196587
  • (MiAaPQ)EBC1681633
  • (WSP)00005298
  • (EXLCZ)991000000000537895
Label
Metal ions and neurodegenerative disorders, editor, Paolo Zatta, (electronic resource)
Publication
Note
Description based upon print version of record
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
cr
Content category
text
Content type code
txt
Contents
  • Contents ; Preface ; List of Contributors ; Chapter 1. Metal-Catalyzed Redox Activity in Neurodegenerative Disease ; 1. INTRODUCTION ; 1.1. Redox-Active Transition Metals in AD ; 1.2. Aggregation of Amyloid-B and Amyloid B Protein Precursor/Amyloid-p-Linked ROS Production
  • 1.3. Iron in Neurodegenerative Disease 1.4. Iron-Mediated Oxidative Stress in Parkinson's Disease ; 1.5. Manganese and Parkinson's Disease ; 1.6. Antioxidant and Transition Metal Homeostasis ; 1.7. CuZnSOD Mutations and Familial Amyotrophic Lateral Sclerosis ; 2. CONCLUSIONS
  • Chapter 2. Metals Distribution and Regionalization in the Brain 1. TRACE ELEMENT DISTRIBUTION IN NORMAL HUMAN BRAIN ; 1.1. Aluminum Iron Copper and Zinc Distribution in Normal Human Brain Sites in Relation to Age ; 1.2. Aluminum ; 1.3. Iron ; 1.4. Copper ; 1.5. Zinc
  • 2. TRACE ELEMENT IMBALANCES IN NEURODEGENERATIVE DISEASES 2.1. Aluminum Iron Copper and Zinc in Alzheimer's Disease ; 2.2. Factors Affecting the Final Results ; 2.3. Aluminum Iron Copper and Zinc in Parkinson's Disease
  • 2.4. Aluminum Iron Copper and Zinc in Western Pacific Parkinsonism-Dementia 2.5. Aluminum Iron Copper and Zinc in Amyotrophic Lateral Sclerosis ; 3. FINAL REMARKS ; Chapter 3. The Olfactory Pathway as a Route of Entry of Metals into the Brain ; 1. INTRODUCTION
  • 2. ANATOMY OF THE OLFACTORY SYSTEM
Dimensions
unknown
Extent
1 online resource (538 p.)
Form of item
online
Isbn
9781281956088
Media category
computer
Media type code
c
Specific material designation
remote
System control number
  • (CKB)1000000000537895
  • (EBL)1681633
  • (OCoLC)815755899
  • (SSID)ssj0000201641
  • (PQKBManifestationID)11184391
  • (PQKBTitleCode)TC0000201641
  • (PQKBWorkID)10245481
  • (PQKB)10196587
  • (MiAaPQ)EBC1681633
  • (WSP)00005298
  • (EXLCZ)991000000000537895

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