The Resource Non-Natural Nucleic Acids : Methods and Protocols, edited by Nathaniel Shank, (electronic resource)

Non-Natural Nucleic Acids : Methods and Protocols, edited by Nathaniel Shank, (electronic resource)

Label
Non-Natural Nucleic Acids : Methods and Protocols
Title
Non-Natural Nucleic Acids
Title remainder
Methods and Protocols
Statement of responsibility
edited by Nathaniel Shank
Contributor
Editor
Editor
Subject
Language
eng
Summary
This volume provides relevant synthetic strategies, incorporation, and applications of non-natural nucleic acids. Chapters detail monomer synthesis, oligomer synthesis/construction, and applications allowing researchers to explore and determine which methodology or methodologies are relevant to their needs. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Non-Natural Nucleic Acids: Methods and Protocols aims to serve as a guide for researchers exploring their own inquiries and to provide a springboard for new endeavors
Member of
Dewey number
572.84
http://bibfra.me/vocab/relation/httpidlocgovvocabularyrelatorsedt
3h3h-dbu8kw
Image bit depth
0
LC call number
QD433-436
Literary form
non fiction
http://library.link/vocab/relatedWorkOrContributorName
Shank, Nathaniel.
Series statement
Methods in Molecular Biology,
Series volume
1973
http://library.link/vocab/subjectName
  • Nucleic acids
  • Genetics
  • Nucleic Acid Chemistry
  • Genetics and Genomics
Label
Non-Natural Nucleic Acids : Methods and Protocols, edited by Nathaniel Shank, (electronic resource)
Instantiates
Publication
Antecedent source
mixed
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Synthesis and Enzymatic Characterization of Sugar-Modified Nucleoside Triphosphate Analogs -- Synthesis of Site-Specific Crown Ether Adducts to DNA Abasic Sites, 8-Oxo-7,8-Dihydro-2’-Deoxyguanosine and 2’-Deoxycytidine -- Synthesis of a Fluorescent Cytidine TNA Triphosphate Analogue -- Synthesis of Base-Modified dNTPs through Cross-Coupling Reactions and Their Polymerase Incorporation to DNA -- 2ʹ-C,4ʹ-C-Ethyleneoxy-Bridged 2ʹ-Deoxyribonucleic Acids (EoDNAs) with Thymine Nucleobases: Synthesis, Duplex-Forming Ability, and Enzymatic Stability -- Synthesis Protocols for Simple Uncharged Glycol Carbamate Nucleic Acids -- Synthesis of Nucleobase-Functionalized Morpholino Monomers -- Synthesis and Application of LKγT Peptide Nucleic Acids -- Aminoglycoside Functionalization as a Tool for Targeting Nucleic Acids -- Preparation and Purification of Oligodeoxynucleotide Duplexes Containing a Site-Specific, Reduced, Chemically-Stable Covalent Interstrand Cross-Link between a Guanine Residue and an Abasic Site -- Copper-Catalyzed Alkyne-Azide Cycloaddition on the Solid Phase for the Preparation of Fully Click-Modified Nucleic Acids -- Labeling Peptide Nucleic Acids with Indium-111 -- Site-Specific Labeling of DNA via PCR with an Expanded Genetic Alphabet -- Flexible Nucleic Acids (FNAs) As Informational Molecules: Enzymatic Polymerization of fNTPs on DNA Templates and Nonenzymatic Oligomerization of RNA on FNA Templates -- Artificial Nucleosides as Diagnostic Probes to Measure Translesion DNA Synthesis -- FRET Assay for Ligands Targeting the Bacterial A-Site RNA -- The Use of Serinol Nucleic Acids as Ultrasensitive Molecular Beacons -- Oligonucleotide Primers with G8AE-Clamp Modifications for RT-qPCR Detection of the Low-Copy dsRNA -- Determining Steady-State Kinetics of DNA Polymerase Nucleotide Incorporation
Dimensions
unknown
Edition
1st ed. 2019.
Extent
1 online resource (XI, 315 p. 95 illus., 41 illus. in color.)
File format
multiple file formats
Form of item
online
Isbn
9781493992164
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-1-4939-9216-4
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote
System control number
  • (CKB)4100000007992535
  • (DE-He213)978-1-4939-9216-4
  • (EXLCZ)994100000007992535
Label
Non-Natural Nucleic Acids : Methods and Protocols, edited by Nathaniel Shank, (electronic resource)
Publication
Antecedent source
mixed
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Synthesis and Enzymatic Characterization of Sugar-Modified Nucleoside Triphosphate Analogs -- Synthesis of Site-Specific Crown Ether Adducts to DNA Abasic Sites, 8-Oxo-7,8-Dihydro-2’-Deoxyguanosine and 2’-Deoxycytidine -- Synthesis of a Fluorescent Cytidine TNA Triphosphate Analogue -- Synthesis of Base-Modified dNTPs through Cross-Coupling Reactions and Their Polymerase Incorporation to DNA -- 2ʹ-C,4ʹ-C-Ethyleneoxy-Bridged 2ʹ-Deoxyribonucleic Acids (EoDNAs) with Thymine Nucleobases: Synthesis, Duplex-Forming Ability, and Enzymatic Stability -- Synthesis Protocols for Simple Uncharged Glycol Carbamate Nucleic Acids -- Synthesis of Nucleobase-Functionalized Morpholino Monomers -- Synthesis and Application of LKγT Peptide Nucleic Acids -- Aminoglycoside Functionalization as a Tool for Targeting Nucleic Acids -- Preparation and Purification of Oligodeoxynucleotide Duplexes Containing a Site-Specific, Reduced, Chemically-Stable Covalent Interstrand Cross-Link between a Guanine Residue and an Abasic Site -- Copper-Catalyzed Alkyne-Azide Cycloaddition on the Solid Phase for the Preparation of Fully Click-Modified Nucleic Acids -- Labeling Peptide Nucleic Acids with Indium-111 -- Site-Specific Labeling of DNA via PCR with an Expanded Genetic Alphabet -- Flexible Nucleic Acids (FNAs) As Informational Molecules: Enzymatic Polymerization of fNTPs on DNA Templates and Nonenzymatic Oligomerization of RNA on FNA Templates -- Artificial Nucleosides as Diagnostic Probes to Measure Translesion DNA Synthesis -- FRET Assay for Ligands Targeting the Bacterial A-Site RNA -- The Use of Serinol Nucleic Acids as Ultrasensitive Molecular Beacons -- Oligonucleotide Primers with G8AE-Clamp Modifications for RT-qPCR Detection of the Low-Copy dsRNA -- Determining Steady-State Kinetics of DNA Polymerase Nucleotide Incorporation
Dimensions
unknown
Edition
1st ed. 2019.
Extent
1 online resource (XI, 315 p. 95 illus., 41 illus. in color.)
File format
multiple file formats
Form of item
online
Isbn
9781493992164
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-1-4939-9216-4
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote
System control number
  • (CKB)4100000007992535
  • (DE-He213)978-1-4939-9216-4
  • (EXLCZ)994100000007992535

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