The Resource Peptide Modifications to Increase Metabolic Stability and Activity, edited by Predrag Cudic, (electronic resource)

Peptide Modifications to Increase Metabolic Stability and Activity, edited by Predrag Cudic, (electronic resource)

Label
Peptide Modifications to Increase Metabolic Stability and Activity
Title
Peptide Modifications to Increase Metabolic Stability and Activity
Statement of responsibility
edited by Predrag Cudic
Contributor
Editor
Editor
Subject
Language
  • eng
  • eng
Summary
In Peptide Modifications to Increase Metabolic Stability and Activity, expert researchers in the field provide summarized methods for preparation, purification of modified peptides, and assessment of their biochemical activities. These methods and protocols include preparation of conformationally constrained peptides, modification of peptide bonds, introduction of nonproteinogenic amino acids, and alteration of peptides’ physical and biological properties by modification of the amino acid side chains and/or terminal residues. With additional chapter that describes new experimental approach for the detection of exogenous peptides within living cells using peptides labeled with heavy isotopes and confocal Raman microscopy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Peptide Modifications to Increase Metabolic Stability and Activity seeks to provide scientists with alternative approaches to peptide modification that many researchers may find applicable to their specific research requirements
Member of
Dewey number
612/.015756
http://bibfra.me/vocab/relation/httpidlocgovvocabularyrelatorsedt
K8hSHw5lwRU
Image bit depth
0
Language note
English
LC call number
  • QH345
  • QD415-436
Literary form
non fiction
http://library.link/vocab/relatedWorkOrContributorName
Cudic, Predrag.
Series statement
Methods in Molecular Biology,
Series volume
1081
http://library.link/vocab/subjectName
  • Biochemistry
  • Nucleic acids
  • Biochemistry, general
  • Nucleic Acid Chemistry
Label
Peptide Modifications to Increase Metabolic Stability and Activity, edited by Predrag Cudic, (electronic resource)
Instantiates
Publication
Note
Bibliographic Level Mode of Issuance: Monograph
Antecedent source
mixed
Carrier category
online resource
Carrier category code
  • cr
Color
not applicable
Content category
text
Content type code
  • txt
Contents
Hantzsch Based Macrocyclization Approach for the Synthesis of Thiazole Containing Cyclopeptides -- The Chemical Synthesis of α-Conotoxins and Structurally Modified Analogs with Enhanced Biological Stability -- Synthesis of AApeptides -- Peptoids and Peptide – Peptoid Hybrid Biopolymers as Peptidomimetics -- Synthesis of Side Chain N,N′-diaminoalkylated Derivatives of Basic Amino Acids for Application in Solid-phase Peptide Synthesis -- Study Protein Folding and Aggregation Using Non-natural Amino Acid p-cyanophenylalanine as a Sensitive Optical Probe -- AdamantoyLated Biologically Active Small Peptides and Glycopeptides Structurally Related to the Bacterial Peptidoglycan -- Optimization of Physicochemical and Pharmacological Properties of Peptide Drugs by Glycosylation -- The Maillard Reaction Induced Modification of Endogenous Opioid Peptide Encephalin -- Solid-phase Guanidinylation of Peptidyl Amines Compatible with Standard Fmoc-chemistry: Formation of Monosubstituted Guanidines -- Stabilization of Collagen-Model, Triple-Helical Peptides for In Vitro and In Vivo Applications -- Identification of Adipokine Receptor Agonists and Turning Them to Antagonists -- Peptide Detection and Structure Determination in Live Cells using Confocal Raman
Dimensions
unknown
Edition
1st ed. 2013.
Extent
1 online resource (IX, 241 p. 92 illus., 16 illus. in color.)
File format
multiple file formats
Form of item
online
Isbn
9781627036528
Level of compression
uncompressed
Media category
computer
Media type code
  • c
Other control number
10.1007/978-1-62703-652-8
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote
System control number
  • (CKB)2670000000433969
  • (SSID)ssj0001294138
  • (PQKBManifestationID)12444815
  • (PQKBTitleCode)TC0001294138
  • (PQKBWorkID)11317354
  • (PQKB)11421970
  • (DE-He213)978-1-62703-652-8
  • (EXLCZ)992670000000433969
Label
Peptide Modifications to Increase Metabolic Stability and Activity, edited by Predrag Cudic, (electronic resource)
Publication
Note
Bibliographic Level Mode of Issuance: Monograph
Antecedent source
mixed
Carrier category
online resource
Carrier category code
  • cr
Color
not applicable
Content category
text
Content type code
  • txt
Contents
Hantzsch Based Macrocyclization Approach for the Synthesis of Thiazole Containing Cyclopeptides -- The Chemical Synthesis of α-Conotoxins and Structurally Modified Analogs with Enhanced Biological Stability -- Synthesis of AApeptides -- Peptoids and Peptide – Peptoid Hybrid Biopolymers as Peptidomimetics -- Synthesis of Side Chain N,N′-diaminoalkylated Derivatives of Basic Amino Acids for Application in Solid-phase Peptide Synthesis -- Study Protein Folding and Aggregation Using Non-natural Amino Acid p-cyanophenylalanine as a Sensitive Optical Probe -- AdamantoyLated Biologically Active Small Peptides and Glycopeptides Structurally Related to the Bacterial Peptidoglycan -- Optimization of Physicochemical and Pharmacological Properties of Peptide Drugs by Glycosylation -- The Maillard Reaction Induced Modification of Endogenous Opioid Peptide Encephalin -- Solid-phase Guanidinylation of Peptidyl Amines Compatible with Standard Fmoc-chemistry: Formation of Monosubstituted Guanidines -- Stabilization of Collagen-Model, Triple-Helical Peptides for In Vitro and In Vivo Applications -- Identification of Adipokine Receptor Agonists and Turning Them to Antagonists -- Peptide Detection and Structure Determination in Live Cells using Confocal Raman
Dimensions
unknown
Edition
1st ed. 2013.
Extent
1 online resource (IX, 241 p. 92 illus., 16 illus. in color.)
File format
multiple file formats
Form of item
online
Isbn
9781627036528
Level of compression
uncompressed
Media category
computer
Media type code
  • c
Other control number
10.1007/978-1-62703-652-8
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote
System control number
  • (CKB)2670000000433969
  • (SSID)ssj0001294138
  • (PQKBManifestationID)12444815
  • (PQKBTitleCode)TC0001294138
  • (PQKBWorkID)11317354
  • (PQKB)11421970
  • (DE-He213)978-1-62703-652-8
  • (EXLCZ)992670000000433969

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