The Resource Retreatment, switching and extended therapy with boceprevir and telaprevir for chronic hepatitis C infection : a review of the clinical effectiveness and safety, [prepared by Canadian Agency for Drugs and Technologies in Health], (electronic resource)

Retreatment, switching and extended therapy with boceprevir and telaprevir for chronic hepatitis C infection : a review of the clinical effectiveness and safety, [prepared by Canadian Agency for Drugs and Technologies in Health], (electronic resource)

Label
Retreatment, switching and extended therapy with boceprevir and telaprevir for chronic hepatitis C infection : a review of the clinical effectiveness and safety
Title
Retreatment, switching and extended therapy with boceprevir and telaprevir for chronic hepatitis C infection
Title remainder
a review of the clinical effectiveness and safety
Statement of responsibility
[prepared by Canadian Agency for Drugs and Technologies in Health]
Contributor
Subject
Genre
Language
eng
Summary
Two new protease inhibitors, boceprevir and telaprevir, were recently approved by Health Canada for treatment of chronic hepatitis C infection, genotype 1. By their current indications, these agents are to be added to peginterferon-ribavirin (PR) therapy. Although within the same drug class, the two new protease inhibitors were studied in different clinical trial programs, and it is not entirely clear what differences exist between the two agents. Evidence relating to prolongation of protease inhibitor therapy beyond the duration approved in the product monographs may also be of interest for patients experiencing inadequate response to therapy. There is also a dilemma as to where to position these new protease inhibitors with respect to existing PR therapy, particularly in treatment-naïve patients. It may therefore be important to understand the efficacy and safety of adding a protease inhibitor after initiation of a PR regimen. The information in this review is intended to support jurisdictions across Canada in their listing decisions on the protease inhibitors for hepatitis C. This report was reviewed by a clinical expert in hepatology
Member of
Cataloging source
CaBNVSL
Dewey number
572/.76
Illustrations
illustrations
Index
no index present
LC call number
QP609.P78
LC item number
R487 2012eb
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
NLM call number
QU 136
NLM item number
R487 2012eb
http://library.link/vocab/relatedWorkOrContributorName
  • Canadian Agency for Drugs and Technologies in Health
  • Canadian Electronic Library (Firm)
Series statement
Rapid response report, summary with critical appraisal
http://library.link/vocab/subjectName
  • Protease inhibitors
  • Hepatitis C
  • Chemotherapy, Combination
  • Protease Inhibitors
  • Hepatitis C
  • Drug Therapy, Combination
Label
Retreatment, switching and extended therapy with boceprevir and telaprevir for chronic hepatitis C infection : a review of the clinical effectiveness and safety, [prepared by Canadian Agency for Drugs and Technologies in Health], (electronic resource)
Link
http://www.deslibris.ca/ID/231805
Instantiates
Publication
Note
  • "8 March 2012"
  • Issued as part of the desLibris documents collection
Antecedent source
not applicable
Bibliography note
Includes bibliographical references (p. 10-11)
Color
multicolored
Dimensions
unknown
Extent
1 electronic text (20 p.)
Form of item
online
Other physical details
tables, digital file.
Publisher number
231805
Specific material designation
remote
System control number
  • (CaBNVSL)gtp00551633
  • (OCoLC)793583271
  • (CaOOCEL)231805
System details
Mode of access: World Wide Web
Label
Retreatment, switching and extended therapy with boceprevir and telaprevir for chronic hepatitis C infection : a review of the clinical effectiveness and safety, [prepared by Canadian Agency for Drugs and Technologies in Health], (electronic resource)
Link
http://www.deslibris.ca/ID/231805
Publication
Note
  • "8 March 2012"
  • Issued as part of the desLibris documents collection
Antecedent source
not applicable
Bibliography note
Includes bibliographical references (p. 10-11)
Color
multicolored
Dimensions
unknown
Extent
1 electronic text (20 p.)
Form of item
online
Other physical details
tables, digital file.
Publisher number
231805
Specific material designation
remote
System control number
  • (CaBNVSL)gtp00551633
  • (OCoLC)793583271
  • (CaOOCEL)231805
System details
Mode of access: World Wide Web

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