The Resource The Molecular Basis of Cancer

The Molecular Basis of Cancer

Label
The Molecular Basis of Cancer
Title
The Molecular Basis of Cancer
Contributor
Subject
Language
  • eng
  • eng
Cataloging source
AU-PeEL
Dewey number
616.99
Language note
English
LC call number
RC268.5
Nature of contents
dictionaries
http://library.link/vocab/relatedWorkOrContributorDate
1936-2019
http://library.link/vocab/relatedWorkOrContributorName
  • Mendelsohn, John
  • Gray, Joe W
  • Howley, Peter M
  • Israel, Mark A
  • Thompson, Craig B
http://library.link/vocab/subjectName
  • Neoplasms
  • Neoplasms
  • Molecular Targeted Therapy
  • Molecular Biology
  • Molecular biology -- Methods
  • Molecular targeted therapy
  • Neoplasms -- Genetics
  • Neoplasms -- Pathology
  • Medicine
  • Health & Biological Sciences
  • Oncology
Label
The Molecular Basis of Cancer
Instantiates
Publication
Note
Description based upon print version of record
Carrier category
online resource
Carrier category code
cr
Content category
text
Content type code
txt
Contents
  • Front Cover; IFC; The Molecular Basis of Cancer; Copyright; Dedication; Contributors; Preface; Contents; I Carcinogenesis and cancer Genetics; Chapter 1 - Cancer: A Genetic Disorder; The Discovery of Cellular Oncogenes; Multistep Tumorigenesis; The Discovery of Tumor Suppressor Genes; Guardians of the Genome; Epigenetic Mechanisms Leading to Loss of Gene Function; Immortalized Proliferation; Non-genetic Mechanisms Accelerating Multistep Tumor Progression; Invasive and Metastatic Behaviors; Other Phenotypes of Neoplasia; References; Chapter 2 - Oncogenes and Signal Transduction
  • Signaling: An Overview; Oncogenes; Signal Transduction by Protein Tyrosine Kinase Receptors; Signaling Pathways of Tyrosine Kinase Receptors; Oncogenes and Survival Signaling; Cytokine Receptor Signaling; Neurotransmitters; Wnt Signaling; Hedgehog/Patched Signaling; Implications for Cancer Therapy; References; Chapter 3 - Tumor Suppressor Genes; Introduction; Complications of Tumor Suppression; Interconnecting the pRB, p53, and mTORC1 Pathways; Epigenetic Modifications and Tumor Suppression; Conclusions; References; Chapter 4 - DNA Repair Pathways and Human Cancer; Introduction
  • The Spectrum of DNA Damage; The Systematic Study of DNA Repair; DNA Repair and the DNA Damage Response; Prognostic and Predictive DNA Repair Biomarkers in Cancer Treatment; The Development of New DNA Repair Biomarkers; Multiple Mechanisms of Cisplatin Resistance; Conclusion; References; Chapter 5 - Epigenetics and Cancer; The Molecular Basis for Epigenetic Control of Gene Expression; Abnormalities of DNA Methylation and Chromatin Organization in Cancer: The Cancer "Epigenome"; Translational Implications of Epigenetic Changes in Cancer; References; Chapter 6 - Infectious Agents and Cancer
  • Overview of Cancer and Infectious Agents; Viruses and Cancer; Bacteria and Cancer; Parasites and Cancer; Perspectives; References; Chapter 7 - Environmental Carcinogenesis; Introduction to Cancer and the Environment; Causes of Cancer; Classes and Types of Carcinogens; Mechanisms of Chemical Carcinogenesis; Endogenous Defense Systems against Chemical Carcinogenesis; Cancer Prevention; Summary and Conclusions; References; Chapter 8 - Animal Models: Flies, Fish, and Yeast; Why Use a Simple Model Organism?; Genetic Conservation and Synteny; Forward Genetics, Reverse Genetics, and Transgenesis
  • Drug Screens; Conditional Models; Yeast; Flies; Fish; Conclusion; References; Chapter 9 - Genetic Mouse Models of Cancer; Basis for Mouse Models of Cancer; Mouse Models of Cancer; Applications of Mouse Models to Cancer Biology; Future Directions of Cancer Models; Conclusions; References; IICancer biology; Chapter 10 - Cancer Stem Cells and the Microenvironment; Identification of Cancer Stem Cells; Cytokine Networks Can Promote Cancer Stem Cell Self-Renewal; Summary; References; CHAPTER 11 - Regulation of the Cell Cycle; Basic Principles of Cell Cycle Progression; The Cyclin-Dependent Kinases
  • Posttranslational Regulation of CDKs
Dimensions
unknown
Edition
4th ed.
Extent
1 online resource (1040 p.)
Form of item
electronic
Isbn
9780323261968
Media category
computer
Media type code
c
Specific material designation
remote
System control number
  • (CKB)2670000000525539
  • (EBL)1746438
  • (OCoLC)884647131
  • (SSID)ssj0001107628
  • (PQKBManifestationID)12470147
  • (PQKBTitleCode)TC0001107628
  • (PQKBWorkID)11085318
  • (PQKB)10624767
  • (EXLCZ)992670000000525539
Label
The Molecular Basis of Cancer
Publication
Note
Description based upon print version of record
Carrier category
online resource
Carrier category code
cr
Content category
text
Content type code
txt
Contents
  • Front Cover; IFC; The Molecular Basis of Cancer; Copyright; Dedication; Contributors; Preface; Contents; I Carcinogenesis and cancer Genetics; Chapter 1 - Cancer: A Genetic Disorder; The Discovery of Cellular Oncogenes; Multistep Tumorigenesis; The Discovery of Tumor Suppressor Genes; Guardians of the Genome; Epigenetic Mechanisms Leading to Loss of Gene Function; Immortalized Proliferation; Non-genetic Mechanisms Accelerating Multistep Tumor Progression; Invasive and Metastatic Behaviors; Other Phenotypes of Neoplasia; References; Chapter 2 - Oncogenes and Signal Transduction
  • Signaling: An Overview; Oncogenes; Signal Transduction by Protein Tyrosine Kinase Receptors; Signaling Pathways of Tyrosine Kinase Receptors; Oncogenes and Survival Signaling; Cytokine Receptor Signaling; Neurotransmitters; Wnt Signaling; Hedgehog/Patched Signaling; Implications for Cancer Therapy; References; Chapter 3 - Tumor Suppressor Genes; Introduction; Complications of Tumor Suppression; Interconnecting the pRB, p53, and mTORC1 Pathways; Epigenetic Modifications and Tumor Suppression; Conclusions; References; Chapter 4 - DNA Repair Pathways and Human Cancer; Introduction
  • The Spectrum of DNA Damage; The Systematic Study of DNA Repair; DNA Repair and the DNA Damage Response; Prognostic and Predictive DNA Repair Biomarkers in Cancer Treatment; The Development of New DNA Repair Biomarkers; Multiple Mechanisms of Cisplatin Resistance; Conclusion; References; Chapter 5 - Epigenetics and Cancer; The Molecular Basis for Epigenetic Control of Gene Expression; Abnormalities of DNA Methylation and Chromatin Organization in Cancer: The Cancer "Epigenome"; Translational Implications of Epigenetic Changes in Cancer; References; Chapter 6 - Infectious Agents and Cancer
  • Overview of Cancer and Infectious Agents; Viruses and Cancer; Bacteria and Cancer; Parasites and Cancer; Perspectives; References; Chapter 7 - Environmental Carcinogenesis; Introduction to Cancer and the Environment; Causes of Cancer; Classes and Types of Carcinogens; Mechanisms of Chemical Carcinogenesis; Endogenous Defense Systems against Chemical Carcinogenesis; Cancer Prevention; Summary and Conclusions; References; Chapter 8 - Animal Models: Flies, Fish, and Yeast; Why Use a Simple Model Organism?; Genetic Conservation and Synteny; Forward Genetics, Reverse Genetics, and Transgenesis
  • Drug Screens; Conditional Models; Yeast; Flies; Fish; Conclusion; References; Chapter 9 - Genetic Mouse Models of Cancer; Basis for Mouse Models of Cancer; Mouse Models of Cancer; Applications of Mouse Models to Cancer Biology; Future Directions of Cancer Models; Conclusions; References; IICancer biology; Chapter 10 - Cancer Stem Cells and the Microenvironment; Identification of Cancer Stem Cells; Cytokine Networks Can Promote Cancer Stem Cell Self-Renewal; Summary; References; CHAPTER 11 - Regulation of the Cell Cycle; Basic Principles of Cell Cycle Progression; The Cyclin-Dependent Kinases
  • Posttranslational Regulation of CDKs
Dimensions
unknown
Edition
4th ed.
Extent
1 online resource (1040 p.)
Form of item
electronic
Isbn
9780323261968
Media category
computer
Media type code
c
Specific material designation
remote
System control number
  • (CKB)2670000000525539
  • (EBL)1746438
  • (OCoLC)884647131
  • (SSID)ssj0001107628
  • (PQKBManifestationID)12470147
  • (PQKBTitleCode)TC0001107628
  • (PQKBWorkID)11085318
  • (PQKB)10624767
  • (EXLCZ)992670000000525539

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