The Resource The epigenetics of autoimmunity, edited by Rongxin Zhang, Department of Immunology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China

The epigenetics of autoimmunity, edited by Rongxin Zhang, Department of Immunology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China

Label
The epigenetics of autoimmunity
Title
The epigenetics of autoimmunity
Statement of responsibility
edited by Rongxin Zhang, Department of Immunology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China
Contributor
Editor
Subject
Language
eng
Summary
The Epigenetics of Autoimmunity covers a topic directly related to translational epigenetics. Via epigenetic mechanisms, a number of internal and external environmental risk factors, including smoking, nutrition, viral infection and the exposure to chemicals, could exert their influence on the pathogenesis of autoimmune diseases. Such factors could impact the epigenetic mechanisms, which, in turn, build relationship with the regulation of gene expression, and eventually triggering immunologic events that result in instability of immune system. Since epigenetic aberrations are known to play a key role in a long list of human diseases, the translational significance of autoimmunity epigenetics is very high. To bridge the gap between environmental and genetic factors, over the past few years, great progress has been made in identifying detailed epigenetic mechanisms for autoimmune diseases. Furthermore, with rapid advances in technological development, high-throughput screening approaches and other novel technologies support the systematic investigations and facilitate the epigenetic identification. This book covers autoimmunity epigenetics from a disease-oriented perspective and several chapters are presented that provide advances in wide-spread disorders or diseases such as systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), multiple sclerosis (MS), type 1 diabetes (T1DM), systemic sclerosis (SSc), primary SjïÅưgren's syndrome (pSS) and autoimmune thyroid diseases (AITDs). These emerging epigenetic studies provide new insights into autoimmune diseases, raising great expectations among researchers and clinicians. This seminal book on this topic comprehensively covers the most recent advances in this exciting and rapidly developing new science. They might reveal not only new clinical biomarkers for diagnosis and disease progression, but also novel targets for potential epigenetic therapeutic treatment
Member of
Cataloging source
NhCcYBP
Dewey number
571.9/73
Illustrations
illustrations
Index
index present
LC call number
QR188.3
LC item number
.E65 2018
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
http://library.link/vocab/relatedWorkOrContributorName
  • Zhang, Rongxin
  • EBSCOhost
Series statement
Translational epigenetics series
Series volume
volume 5
http://library.link/vocab/subjectName
  • Autoimmunity
  • Autoimmune diseases
  • Epigenesis
  • Autoimmunity
  • Epigenesis, Genetic
Label
The epigenetics of autoimmunity, edited by Rongxin Zhang, Department of Immunology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China
Link
http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=1172392
Instantiates
Publication
Copyright
Antecedent source
unknown
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
1. The epigenetics of autoimmunity: an overview -- 2. Immune cell development and epigenetics -- 3. DNA methylation and histone modifications in autoimmunity -- 4. MicroRNA and T helper cell-mediated immune responses -- 5. Long noncoding RNAs in the immune response -- 6. Epigenetics of systemic lupus erythematosus -- 7. Rheumatoid arthritis and epigenetics -- 8. Epigenetic modifications in multiple sclerosis pathophysiology: potential diagnostic and therapeutic applications -- 9. Type 1 diabetes and epigenetics -- 10. Systemic sclerosis and epigenetics -- 11. Primary Sjogren's syndrome and epigenetics -- 12. Autoimmune thyroid diseases and epigenetics -- 13. The epigenetics of primary biliary cholangitis -- 14. Immune-mediated pulmonary disease and epigenetics -- 15. The epigenetics of autoimmunity and epigenetic drug discovery -- 16. Treatment of autoimmune diseases and prevention of transplant rejection and graft-versus-host disease by regulatory T cells: the state of the art and perspectives -- 17. Noncoding RNA-targeted therapeutics in autoimmune diseases: from bench to bedside -- 18. Future challenges and prospects for the epigenetics of autoimmunity -- Index
Dimensions
unknown
Extent
1 online resource.
File format
unknown
Form of item
online
Isbn
9780128099285
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Quality assurance targets
not applicable
Reformatting quality
unknown
Reproduction note
Electronic reproduction.
Sound
unknown sound
Specific material designation
remote
Stock number
9780128099285
System control number
(NhCcYBP)40029586779
Label
The epigenetics of autoimmunity, edited by Rongxin Zhang, Department of Immunology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China
Link
http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=1172392
Publication
Copyright
Antecedent source
unknown
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
1. The epigenetics of autoimmunity: an overview -- 2. Immune cell development and epigenetics -- 3. DNA methylation and histone modifications in autoimmunity -- 4. MicroRNA and T helper cell-mediated immune responses -- 5. Long noncoding RNAs in the immune response -- 6. Epigenetics of systemic lupus erythematosus -- 7. Rheumatoid arthritis and epigenetics -- 8. Epigenetic modifications in multiple sclerosis pathophysiology: potential diagnostic and therapeutic applications -- 9. Type 1 diabetes and epigenetics -- 10. Systemic sclerosis and epigenetics -- 11. Primary Sjogren's syndrome and epigenetics -- 12. Autoimmune thyroid diseases and epigenetics -- 13. The epigenetics of primary biliary cholangitis -- 14. Immune-mediated pulmonary disease and epigenetics -- 15. The epigenetics of autoimmunity and epigenetic drug discovery -- 16. Treatment of autoimmune diseases and prevention of transplant rejection and graft-versus-host disease by regulatory T cells: the state of the art and perspectives -- 17. Noncoding RNA-targeted therapeutics in autoimmune diseases: from bench to bedside -- 18. Future challenges and prospects for the epigenetics of autoimmunity -- Index
Dimensions
unknown
Extent
1 online resource.
File format
unknown
Form of item
online
Isbn
9780128099285
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Quality assurance targets
not applicable
Reformatting quality
unknown
Reproduction note
Electronic reproduction.
Sound
unknown sound
Specific material designation
remote
Stock number
9780128099285
System control number
(NhCcYBP)40029586779

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